Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342177 | 0.89 | MAPT (0.43) | ALDH1A1MAPTKDM4ERECQLTDP1 | |
| SCHEMBL7640011 | 0.82 | MAPT (0.47) | ALDH1A1MAPTKDM4ERECQLTDP1 | |
| SCHEMBL341388 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PPARGPPARAKDM4EL3MBTL1 | |
| SCHEMBL124147 | 0.82 | MAPT (0.47) | ALDH1A1MAPTKDM4ERECQLTDP1 | |
| SCHEMBL28401713 | 0.81 | LMNA (0.42) | ALDH1A1MAPTKDM4ERECQLTDP1 | |
| SCHEMBL6051256 | 0.77 | LMNA (0.44) | ALDH1A1MAPTKDM4ERECQLTDP1 | |
| SCHEMBL30898834 | 0.74 | ALDH1A1 (0.44) | ALDH1A1PPARGPPARAKDM4EL3MBTL1 | |
| SCHEMBL694567 | 0.73 | LMNA (0.48) | ALDH1A1MAPTKDM4ERECQLTDP1 | |
| SCHEMBL29145983 | 0.73 | LMNA (0.48) | ALDH1A1PPARGPPARAKDM4ETDP1 | |
| SCHEMBL165837 | 0.73 | OPRD1 (0.39) | L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160073635-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160073635-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | TARS2, TST, TARS1 | ALDH1A1 548/4885PPARG 505/4885PPARA 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.