Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RGS4 | P49798 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146972 | 0.95 | ADORA2B (0.40) | TDP1ADORA2BMEN1KMT2AGAA | |
| SCHEMBL4152333 | 0.85 | TDP1 (0.41) | TDP1L3MBTL1PGRRORARORC | |
| SCHEMBL4156451 | 0.83 | PDE4A (0.43) | TDP1L3MBTL1PGRRORARORC | |
| SCHEMBL7196320 | 0.79 | ADORA2B (0.49) | TDP1ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL4147828 | 0.76 | GSK3B (0.35) | MAPTADORA2APDE4APDE4BPDE4C | |
| SCHEMBL4717518 | 0.70 | TDP1 (0.42) | TDP1L3MBTL1PGRRORARORC | |
| SCHEMBL4150749 | 0.69 | PDE4A (0.42) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3243411 | 0.67 | ALDH1A1 (0.41) | TDP1L3MBTL1PGRRORARORC | |
| SCHEMBL216146 | 0.67 | CNR2 (0.49) | TDP1L3MBTL1PGRRORARORC | |
| SCHEMBL4138900 | 0.66 | HPGD (0.42) | TDP1L3MBTL1PGRRORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048374-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2009-02-19 | — | — | US | disclosed |