Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146852 | 0.95 | TDP1 (0.40) | ADORA2BKMT2AGAAMEN1TDP1 | |
| SCHEMBL7196320 | 0.84 | ADORA2B (0.49) | ADORA2BPTGS1PTGS2MGLLFAAH | |
| SCHEMBL4152333 | 0.81 | TDP1 (0.41) | ADORA2BTLR8GAATDP1USP2 | |
| SCHEMBL4156451 | 0.79 | PDE4A (0.43) | ADORA2BTDP1 | |
| SCHEMBL28435216 | 0.71 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHTLR8 | |
| SCHEMBL28440804 | 0.71 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHTLR8 | |
| SCHEMBL28439331 | 0.71 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHTLR8 | |
| SCHEMBL4148123 | 0.70 | ADRA2A (0.42) | ADORA2BPTGS1PTGS2MGLLFAAH | |
| SCHEMBL4150749 | 0.68 | PDE4A (0.42) | ADORA2BCYP1A2CYP2C19CYP2C9HPGD | |
| SCHEMBL8146236 | 0.68 | TLR8 (0.46) | PTGS1PTGS2MGLLFAAHTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048374-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
| EP-1996649-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | Baerlocher GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007104379-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |