Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22914751 | 0.87 | LMNA (0.64) | SLC6A9SLC6A5KCNH2LMNAMAPT | |
| SCHEMBL709690 | 0.84 | MAPT (0.49) | SLC6A9SLC6A5LMNAMAPTMAPK1 | |
| SCHEMBL532719 | 0.83 | HTT (0.49) | SLC6A9SLC6A5LMNAMAPTMAPK1 | |
| SCHEMBL20524591 | 0.83 | KDM4E (0.44) | SLC6A9SLC6A5KCNH2LMNAMAPT | |
| SCHEMBL29378266 | 0.82 | GPR119 (0.68) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL355131 | 0.82 | GPR119 (0.68) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL632171 | 0.80 | GRM5 (0.59) | LMNAMAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL631389 | 0.80 | RBP4 (0.50) | SLC6A9SLC6A5KCNH2LMNAMAPT | |
| SCHEMBL8415671 | 0.79 | SLC6A9 (0.46) | SLC6A9SLC6A5KCNH2ALDH1A1L3MBTL1 | |
| SCHEMBL6679416 | 0.79 | ALDH1A1 (0.57) | SLC6A9SLC6A5KCNH2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362156-A | Muscarinic receptor 4 antagonists and methods of use | 纽罗克里生物科学有限公司 | 2022-11-18 | — | — | CN | disclosed |
| WO-2009079593-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |