SCHEMBL4148464

SCHEMBL4148464

O=C(O)c1ccccc1-c1ccc(OC(O)CCO)cc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.45
PPARA Q07869 5/20 0.45
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
LTB4R2 Q9NPC1 7/20 0.43
BRS3 P32247 4/20 0.42
LPAR1 Q92633 1/20 0.41
HNF4A P41235 1/20 0.41
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2597797 0.79 ALDH1A1 (0.57) PPARGPPARAFNTAFNTBLTB4R2
SCHEMBL29979341 0.79 MEN1 (0.58) PPARGPPARAFNTAFNTBLTB4R2
SCHEMBL23354195 0.79 MEN1 (0.58) PPARGPPARAFNTAFNTBLTB4R2
SCHEMBL2569853 0.78 ALDH1A1 (0.45) PPARGPPARA
SCHEMBL2385805 0.77 XDH (0.40) PPARGPPARA
SCHEMBL4148459 0.77 ALDH1A1 (0.48) FNTAFNTBLTB4R2BRS3
SCHEMBL28793274 0.76 GAA (0.57) PPARAHTT
SCHEMBL30292805 0.76 HNF4A (0.63) FNTAFNTBLTB4R2HNF4A
SCHEMBL18759613 0.76 HNF4A (0.63) FNTAFNTBLTB4R2HNF4A
SCHEMBL11402358 0.75 GSTP1 (0.56) LTB4R2HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090030218-A1 Method For Producing Aminoalcohol Derivative Having Biphenyl Group KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-01-29 US claimed
EP-1932826-A1 METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP Kissei Pharmaceutical Co., Ltd. (JP) 2008-06-18 EP claimed
US-20090030218-A1 Method For Producing Aminoalcohol Derivative Having Biphenyl Group KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-01-29 US disclosed
EP-1932826-A1 METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP Kissei Pharmaceutical Co., Ltd. (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030218-A1 Method For Producing Aminoalcohol Derivative Having Biphenyl Group ALDH7A1, DDC, ADH5 PPARG 181/4885PPARA 209/4885FNTA 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.