Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194164 | 1.00 | HCRTR1 (0.46) | HCRTR1HCRTR2L3MBTL1CHRM2CHRM1 | |
| SCHEMBL6701246 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2L3MBTL1CHRM2CHRM1 | |
| SCHEMBL4133494 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2L3MBTL1CHRM2CHRM1 | |
| SCHEMBL23878361 | 0.80 | L3MBTL1 (0.50) | HCRTR2L3MBTL1HDAC1HDAC8HDAC6 | |
| SCHEMBL22039448 | 0.80 | L3MBTL1 (0.50) | HCRTR2L3MBTL1HDAC1HDAC8HDAC6 | |
| SCHEMBL4135564 | 0.78 | L3MBTL1 (0.50) | L3MBTL1CHRM2CHRM1 | |
| SCHEMBL4845772 | 0.78 | L3MBTL1 (0.50) | L3MBTL1CHRM2CHRM1 | |
| SCHEMBL7193226 | 0.77 | GPR119 (0.50) | HCRTR1HCRTR2L3MBTL1PDE5ALIPE | |
| SCHEMBL4135463 | 0.74 | HCRTR1 (0.48) | HCRTR1HCRTR2CHRM2CHRM1GRIN2B | |
| SCHEMBL7138721 | 0.74 | HCRTR1 (0.48) | HCRTR1HCRTR2CHRM2CHRM1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLANT ANDREW | 2009-01-08 | — | — | US | disclosed |
| US-7419936-B2 | Optically active 2,5-bisaryl-Δ1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2004-03-25 | — | — | US | disclosed |
| EP-1322587-A1 | METHOD FOR PRODUCING KETOCARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024622-A1 | METHOD FOR PRODUCING KETOCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLD1, RPS3A, AMY1A | HCRTR1 1051/4885HCRTR2 2329/4885L3MBTL1 291/4885 |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | DDT, CRY1, PLD1 | HCRTR1 525/4885HCRTR2 1235/4885L3MBTL1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.