Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620456 | 0.97 | LIPE (0.47) | GPR119LIPEABHD6PDE5AL3MBTL1 | |
| SCHEMBL6701246 | 0.85 | HCRTR1 (0.46) | GPR119PDE5AL3MBTL1SCD5HCRTR1 | |
| SCHEMBL4133494 | 0.85 | HCRTR1 (0.46) | GPR119PDE5AL3MBTL1SCD5HCRTR1 | |
| SCHEMBL7043219 | 0.82 | DRD2 (0.40) | GPR119L3MBTL1 | |
| SCHEMBL7043305 | 0.82 | DRD2 (0.40) | GPR119L3MBTL1 | |
| SCHEMBL22039428 | 0.82 | HTR7 (0.42) | L3MBTL1HCRTR2 | |
| SCHEMBL7236411 | 0.82 | HTR7 (0.42) | L3MBTL1HCRTR2 | |
| SCHEMBL7132988 | 0.82 | AKR1C3 (0.37) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL7233985 | 0.81 | KDM1A (0.46) | GPR119L3MBTL1KDM1A | |
| SCHEMBL6832962 | 0.81 | GPR119 (0.49) | GPR119PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2003-11-27 | — | — | US | disclosed |
| WO-2002081489-A1 | PALLADIUM-COMPLEXES BASED ON PYRROLINE-METAL COMPLEXES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | CYP2F1, HK1, FBP1 | GPR119 1397/4885LIPE 3358/4885ABHD6 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.