Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701246 | 1.00 | HCRTR1 (0.46) | HCRTR1HCRTR2PDE5AL3MBTL1AURKA | |
| SCHEMBL7193226 | 0.85 | GPR119 (0.50) | HCRTR1HCRTR2PDE5AL3MBTL1SCD5 | |
| SCHEMBL4149720 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2PDE5AL3MBTL1AURKA | |
| SCHEMBL7194164 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2PDE5AL3MBTL1AURKA | |
| SCHEMBL5620456 | 0.81 | LIPE (0.47) | HCRTR1HCRTR2PDE5AL3MBTL1SCD5 | |
| SCHEMBL7043551 | 0.80 | AKR1C3 (0.38) | HCRTR1HCRTR2L3MBTL1 | |
| SCHEMBL7077843 | 0.76 | PDE5A (0.43) | HCRTR1HCRTR2PDE5AL3MBTL1AURKA | |
| SCHEMBL7040949 | 0.76 | CA2 (0.40) | L3MBTL1 | |
| SCHEMBL4142332 | 0.75 | HCRTR1 (0.48) | HCRTR1HCRTR2L3MBTL1 | |
| SCHEMBL4135463 | 0.74 | HCRTR1 (0.48) | HCRTR1HCRTR2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLANT ANDREW | 2009-01-08 | — | — | US | disclosed |
| US-7419936-B2 | Optically active 2,5-bisaryl-Δ1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLD1, RPS3A, AMY1A | HCRTR1 1051/4885HCRTR2 2329/4885PDE5A 811/4885 |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | DDT, CRY1, PLD1 | HCRTR1 525/4885HCRTR2 1235/4885PDE5A 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.