SCHEMBL4151183

SCHEMBL4151183

Cc1cccc(-c2c(C)cccc2C=Cc2ccccc2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
GRM4 Q14833 4/20 0.53
KDM4E B2RXH2 4/20 0.53
HPGD P15428 3/20 0.53
RAB9A P51151 3/20 0.53
NPC1 O15118 1/20 0.53
GRM5 P41594 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
MEN1 O00255 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
PKM P14618 1/20 0.53
TSHR P16473 1/20 0.53
NFKB1 P19838 1/20 0.53
CYP2C19 P33261 1/20 0.53
THPO P40225 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4151179 1.00 ALDH1A1 (0.53) ALDH1A1GRM4KDM4EHPGDRAB9A
SCHEMBL4155634 0.83 L3MBTL1 (0.41) GRM4KDM4ERAB9ANPC1PKM
SCHEMBL4155639 0.83 L3MBTL1 (0.41) GRM4KDM4ERAB9ANPC1PKM
SCHEMBL24729625 0.76 CCR1 (0.68) RAB9AMEN1KMT2ACCR1CCR8
SCHEMBL27739023 0.73 CCR1 (0.48) ALDH1A1GRM4KDM4ERAB9ANPC1
SCHEMBL16105782 0.72 RAB9A (0.66) ALDH1A1KDM4EHPGDRAB9AMEN1
SCHEMBL1128126 0.72 RAB9A (0.66) ALDH1A1KDM4EHPGDRAB9AMEN1
SCHEMBL1128128 0.72 RAB9A (0.66) ALDH1A1KDM4EHPGDRAB9AMEN1
SCHEMBL5708105 0.72 KDM4E (0.47) ALDH1A1GRM4KDM4EHPGDRAB9A
SCHEMBL842427 0.71 NFE2L2 (0.50) ALDH1A1GRM4KDM4EHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8212048-B2 Method of producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 US disclosed
CN-101410375-B Process for producing aromatic compound SUMITOMO CO LTD 2012-06-13 CN disclosed
CN-101410375-A Process for producing aromatic compound SUMITOMO CHEMICAL CO (JP) 2009-04-15 CN disclosed
US-20090043096-A1 METHOD OF PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043096-A1 METHOD OF PRODUCING AROMATIC COMPOUND AHR, CYP1A1, ARNT ALDH1A1 779/4885GRM4 3472/4885KDM4E 3177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.