Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303845 | 0.86 | HTR7 (0.49) | DRD2DRD4DRD3FFAR1SCN8A | |
| SCHEMBL1373278 | 0.82 | ALDH1A1 (0.52) | HTR7TRPA1ALDH1A1TSHRBACE1 | |
| SCHEMBL4159809 | 0.82 | CNR1 (0.42) | HTR7ALDH1A1ACMSD | |
| SCHEMBL3636690 | 0.81 | SCN8A (0.49) | DRD2DRD4DRD3FFAR1SCN8A | |
| SCHEMBL7500105 | 0.81 | DRD2 (0.48) | DRD2DRD4DRD3FFAR1SCN8A | |
| SCHEMBL5990056 | 0.81 | HTR7 (0.51) | DRD2DRD4DRD3FFAR1SCN8A | |
| SCHEMBL29628986 | 0.80 | PTPRC (0.55) | DRD2DRD4DRD3FFAR1SCN8A | |
| SCHEMBL12856837 | 0.80 | PTPRC (0.55) | DRD2DRD4DRD3FFAR1SCN8A | |
| SCHEMBL1309108 | 0.79 | TRPA1 (0.43) | HTR7TRPA1ALDH1A1TSHR | |
| SCHEMBL28268408 | 0.79 | ALDH1A1 (0.54) | HTR7TRPA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | disclosed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | disclosed |
| EP-1718653-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | Ligand Pharmaceuticals Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082909-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2005-09-09 | — | — | WO | disclosed |
| US-4536591-A | Insecticidal [1,1'-biphenyl]-3-ylmethyl esters | FMC CORPORATION (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0063374-B1 | SUBSTITUTED BIPHENYL COMPOUNDS | FMC Corporation (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4402973-A | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters | FMC CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |
| EP-0020685-B1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC Corporation (US) | 1983-06-15 | — | — | EP | disclosed |
| EP-0063374-A1 | Substituted biphenyl compounds | FMC Corporation (US) | 1982-10-27 | — | — | EP | disclosed |
| US-4329518-A | INSECTICIDES, ACARICIDES, MITICIDES | FMC CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0049977-A1 | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them | FMC Corporation (US) | 1982-04-21 | — | — | EP | disclosed |
| EP-0020685-A4 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-07-16 | — | — | EP | disclosed |
| EP-0020685-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4214004-A | MITICIDES | FMC CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| WO-1980001163-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC CORP (US) | 1980-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | NR3C1, NR3C2, MC2R | DRD2 2477/4885DRD4 2903/4885DRD3 2662/4885 |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | NR3C1, NR3C2, MC2R | DRD2 2477/4885DRD4 2903/4885DRD3 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.