Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053146 | 0.89 | KIF11 (0.45) | NPC1RAB9ACHRM2KIF11SMN1; SMN2 | |
| SCHEMBL10309879 | 0.89 | KIF11 (0.45) | NPC1RAB9ACHRM2KIF11SMN1; SMN2 | |
| SCHEMBL6302955 | 0.89 | KIF11 (0.45) | NPC1RAB9ACHRM2KIF11SMN1; SMN2 | |
| SCHEMBL2490249 | 0.88 | NPC1 (0.42) | NPC1RAB9AMAPTCHRM2ALDH1A1 | |
| SCHEMBL2489144 | 0.83 | LMNA (0.45) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL2490317 | 0.83 | KIF11 (0.37) | NPC1RAB9AMAPTCHRM2ALDH1A1 | |
| SCHEMBL4160988 | 0.83 | NPC1 (0.39) | NPC1RAB9AMAPTCHRM2ALDH1A1 | |
| SCHEMBL888258 | 0.83 | KIF11 (0.44) | NPC1RAB9AKIF11SMN1; SMN2MEN1 | |
| SCHEMBL9439820 | 0.82 | KIF11 (0.47) | KIF11SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL13772987 | 0.82 | ACHE (0.52) | NPC1RAB9AACHEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182135-A1 | Amino modifiers | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182135-A1 | Amino modifiers | BCAT2, AADAT, BCAT1 | NPC1 4450/4885RAB9A 2724/4885ACHE 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.