Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.64 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.64 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.55 |
| ▸ | F2R | P25116 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529489 | 0.86 | HPGD (0.62) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL28763778 | 0.86 | HPGD (0.53) | TAS1R3TAS1R1TAS1R2P2RX7HPGD | |
| SCHEMBL4148749 | 0.85 | HPGD (0.70) | P2RX7GPR139HPGDALDH1A1 | |
| SCHEMBL13841435 | 0.84 | TAS1R3 (0.50) | TAS1R3TAS1R1TAS1R2P2RX7TSHR | |
| SCHEMBL9491955 | 0.84 | TAS1R3 (0.57) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL11653801 | 0.83 | P2RX7 (0.57) | TAS1R3TAS1R1TAS1R2P2RX7TSHR | |
| SCHEMBL22059502 | 0.83 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL2229856 | 0.83 | TAS1R3 (0.56) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL13754086 | 0.83 | HPGD (0.51) | TAS1R3TAS1R1TAS1R2GPR139TSHR | |
| SCHEMBL11570780 | 0.82 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
| US-20070010509-A1 | Cycloamine ccr5 receptor antagonists | TEIJIN PHARMA LIMITED (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010509-A1 | Cycloamine ccr5 receptor antagonists | CCR5, CCR2, CCR1 | TAS1R3 1735/4885TAS1R1 1302/4885TAS1R2 1779/4885 |
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | PRMT5, CYC1, CBR3 | TAS1R3 2726/4885TAS1R1 2426/4885TAS1R2 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.