Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41021 | 0.90 | CA1 (0.65) | ALDH1A1SMN1; SMN2HPGDCES2CES1 | |
| SCHEMBL12399066 | 0.86 | ACHE (0.71) | ACHENPC1RAB9AALDH1A1SMN1; SMN2 | |
| Methyl Alcohol SCHEMBL20136156 | 0.85 | ACHE (0.88) | ACHENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13925529 | 0.84 | — | — | |
| SCHEMBL19182839 | 0.84 | ACHE (1.00) | ACHENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12464 | 0.84 | — | — | |
| SCHEMBL2758528 | 0.82 | LMNA (0.70) | ACHENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8392489 | 0.82 | ACHE (0.65) | ACHENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL17962460 | 0.82 | ACHE (0.65) | ACHENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL758577 | 0.82 | LMNA (0.70) | ACHENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182135-A1 | Amino modifiers | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182135-A1 | Amino modifiers | BCAT2, AADAT, BCAT1 | ACHE 1503/4885NPC1 4450/4885RAB9A 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.