Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.66 |
| ▸ | PARP1 | P09874 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.66 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.60 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152437 | 0.86 | SIGMAR1 (0.64) | TNKSPARP1ALOX5TNKS2POLH | |
| SCHEMBL7933564 | 0.83 | SIGMAR1 (0.73) | TNKSKDM4ECYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL4160578 | 0.83 | CSNK2A2 (0.81) | TNKSPARP1ALOX5TNKS2POLH | |
| SCHEMBL34405 | 0.80 | TNKS (1.00) | TNKSPARP1ALOX5TNKS2POLH | |
| SCHEMBL29678122 | 0.80 | TNKS (1.00) | TNKSPARP1ALOX5TNKS2POLH | |
| SCHEMBL4160583 | 0.79 | TNKS (0.64) | TNKSPARP1ALOX5TNKS2POLH | |
| SCHEMBL8782354 | 0.79 | BCHE (0.53) | TNKSTNKS2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL2218499 | 0.78 | POLH (0.75) | TNKSPARP1ALOX5TNKS2POLH | |
| SCHEMBL4166843 | 0.78 | CYP1A1 (0.55) | ALDH2MAOAMAOBBCHEACHE | |
| SCHEMBL12757263 | 0.78 | CSNK2A2 (0.74) | TNKSPARP1ALOX5TNKS2POLH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
| US-20020147353-A1 | Novel flavonoids | VERENIGING CHRISTELIJK WETENSCHAPPELIJK ANDERWIJS (NL) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, ABCC8 | TNKS 4638/4885PARP1 2448/4885ALOX5 3590/4885 |
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | TNKS 3218/4885PARP1 2524/4885ALOX5 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.