SCHEMBL4173907

SCHEMBL4173907

CC(=O)Oc1c(-c2ccc(O)cc2)oc2cc(O)c(C(C)=O)c(OC(C)=O)c2c1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 10/20 0.54
CYP2D6 P10635 4/20 0.54
KDM4E B2RXH2 3/20 0.54
POLB P06746 1/20 0.54
APEX1 P27695 1/20 0.54
RECQL P46063 1/20 0.54
MCL1 Q07820 1/20 0.54
POLH Q9Y253 1/20 0.54
ADORA3 P0DMS8 1/20 0.52
ALDH1A1 P00352 2/20 0.49
PTPN1 P18031 1/20 0.49
MEN1 O00255 1/20 0.49
CYP2C9 P11712 1/20 0.49
MAPK1 P28482 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ABCB1 P08183 1/20 0.49
ABCG2 Q9UNQ0 1/20 0.49
MAPT P10636 2/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4152216 0.91 ADORA3 (0.64) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL4156024 0.90 ADORA3 (0.56) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL30627918 0.84 CYP3A4 (0.75) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL30627917 0.84 CYP3A4 (0.75) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL4160544 0.84 CYP3A4 (0.75) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL20699749 0.83 TUBB4A (0.69) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL4153368 0.81 POLH (0.51) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL28428273 0.80 ADORA3 (0.67) CYP3A4CYP2D6KDM4EADORA3ALDH1A1
SCHEMBL4163598 0.79 KDM4E (0.47) CYP3A4CYP2D6KDM4EPOLBAPEX1
SCHEMBL4165750 0.77 POLH (0.47) CYP3A4CYP2D6KDM4EPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130051-A1 Flavonoid Compounds and Uses Thereof HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) 2009-05-21 US claimed
EP-0524744-B1 Base board for printed circuit board MITSUBISHI GAS CHEMICAL CO (JP) 1995-06-21 EP disclosed
US-5266385-A For inspection of printed circuit patterns MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-11-30 US disclosed
EP-0524744-A1 Base board for printed circuit board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090130051-A1 Flavonoid Compounds and Uses Thereof CAT, NQO1, GPX4 CYP3A4 518/4885CYP2D6 297/4885KDM4E 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.