Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16572248 | 0.94 | RARB (0.57) | RARBALDH1A1MAPTMEN1RARA | |
| SCHEMBL4716336 | 0.94 | RARB (0.57) | RARBALDH1A1MAPTMEN1RARA | |
| SCHEMBL219423 | 0.94 | ALDH1A1 (0.52) | RARBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL13618274 | 0.93 | RARB (0.58) | RARBALDH1A1MAPTMEN1RARA | |
| SCHEMBL13617779 | 0.93 | RARB (0.58) | RARBALDH1A1MAPTMEN1RARA | |
| SCHEMBL4454097 | 0.89 | ALDH1A1 (0.47) | RARBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL847304 | 0.88 | ALDH1A1 (0.53) | RARBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5604295 | 0.88 | ALDH1A1 (0.45) | RARBALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11811560 | 0.86 | ESR1 (0.57) | ALDH1A1MEN1KMT2AHSD17B10THRA | |
| SCHEMBL2120077 | 0.86 | ESR1 (0.57) | ALDH1A1MEN1KMT2AHSD17B10THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275334-A1 | LINEAR PEPTIDE ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2017-09-28 | — | — | US | disclosed |
| US-20170275334-A1 | LINEAR PEPTIDE ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2017-09-28 | — | — | US | disclosed |
| US-9708368-B2 | Linear peptide antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708368-B2 | Linear peptide antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160194358-A1 | LINEAR PEPTIDE ANTIBIOTCS | RQX PHARMACEUTICALS, INC. | 2016-07-07 | — | — | US | disclosed |
| US-20160194358-A1 | LINEAR PEPTIDE ANTIBIOTCS | RQX PHARMACEUTICALS, INC. | 2016-07-07 | — | — | US | disclosed |
| US-20150166605-A1 | LINEAR PEPTIDE ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2015-06-18 | — | — | US | disclosed |
| US-20150166605-A1 | LINEAR PEPTIDE ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2015-06-18 | — | — | US | disclosed |
| US-8999922-B2 | Linear peptide antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-8999922-B2 | Linear peptide antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| WO-2010123599-A2 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-10-28 | — | — | WO | disclosed |
| EP-1654247-B1 | ALKYNYL ARYL CARBOXAMIDES | MERCK SERONO SA (CH) | 2010-01-20 | — | — | EP | disclosed |
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | disclosed |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-29 | — | — | US | disclosed |
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | disclosed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | disclosed |
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
| EP-0442266-B1 | Tolan derivatives, liquid crystal compositions containing them, and liquid crystal elements using them | SEIKO EPSON CORP (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5314640-A | Tolan derivatives, liquid crystal compositions including same, liquid crystal display devices including the compositions and method of preparation | SEIKO EPSON CORPORATION (JP) | 1994-05-24 | — | — | US | disclosed |
| EP-0442266-A1 | Tolan derivatives, liquid crystal compositions containing them, and liquid crystal elements using them | SEIKO EPSON CORPORATION (JP) | 1991-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166605-A1 | LINEAR PEPTIDE ANTIBIOTICS | SPAST, PEPD, NPEPPS | RARB 895/4885ALDH1A1 3907/4885MAPT 3572/4885 |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | TNNC1, CPT1B, MUSK | RARB 2698/4885ALDH1A1 200/4885MAPT 4533/4885 |
| US-20170275334-A1 | LINEAR PEPTIDE ANTIBIOTICS | SPAST, PEPD, NPEPPS | RARB 895/4885ALDH1A1 3907/4885MAPT 3572/4885 |
| US-20160194358-A1 | LINEAR PEPTIDE ANTIBIOTCS | ANPEP, NPEPPS, PEPD | RARB 1708/4885ALDH1A1 4344/4885MAPT 3456/4885 |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | ORC3, BRS3, OSBPL3 | RARB 257/4885ALDH1A1 4216/4885MAPT 2833/4885 |
| US-20070105913-A1 | Alkynyl aryl carboxamides | ECHS1, IRS1, HCCS | RARB 4697/4885ALDH1A1 1454/4885MAPT 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.