SCHEMBL4167484

SCHEMBL4167484

C#Cc1cn(C2CC(O)C(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.56
TYMS P04818 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6299993 0.93 TYMS (0.54) TYMPTYMS
SCHEMBL6299997 0.93 TYMS (0.54) TYMPTYMS
SCHEMBL3493524 0.90 TYMP (0.54) TYMPTYMS
SCHEMBL4170246 0.89 HSP90AA1 (0.45) TYMPTYMS
SCHEMBL4179824 0.88 TYMP (0.55) TYMPTYMS
SCHEMBL8326880 0.87 LMNA (0.64) TYMPTYMS
SCHEMBL1727320 0.87 POLB (0.58) TYMP
SCHEMBL10446716 0.87 POLB (0.58) TYMP
SCHEMBL10388602 0.87 TYMP (0.58) TYMPTYMS
SCHEMBL10692639 0.87 TK1 (0.64) TYMPTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090004137-A1 Uridine Derivatives as Antiviral Drugs Against a Flaviviridae, Especially Hcv INSTITUTE NATIONAL DE LA SAINTE ET DE LA RECHDERCHE MEDICALE (FR) 2009-01-01 US disclosed
EP-1674104-A1 Uridine derivatives as antiviral drugs against a flaviviridae, especially HCV INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2006-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090004137-A1 Uridine Derivatives as Antiviral Drugs Against a Flaviviridae, Especially Hcv NUDT1, UMPS, UPP1 TYMP 68/4885TYMS 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.