SCHEMBL4167795

SCHEMBL4167795

NC(=O)Nc1cc(Nc2nc(N)nc(Cl)n2)ccc1/N=N/c1cc2c(S(=O)(=O)O)cc(S(=O)(=O)O)cc2cc1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.46
▸ CHAT P28329 3/20 0.39
▸ USP2 O75604 1/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ ENPP3 O14638 1/20 0.38
▸ ENPP1 P22413 1/20 0.38
▸ NT5E P21589 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ CD40 P25942 1/20 0.37
▸ CD40LG P29965 1/20 0.37
▸ ENPP2 Q13822 6/20 0.36
▸ CARM1 Q86X55 1/20 0.36
▸ PRMT1 Q99873 1/20 0.36
▸ HPGDS O60760 1/20 0.35
▸ CA12 O43570 3/20 0.35
▸ CA1 P00915 3/20 0.35
▸ CA2 P00918 3/20 0.35
▸ CA9 Q16790 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637596 1.00 FUT8 (0.46) FUT8CHATUSP2APEX1ENPP3
SCHEMBL3653222 1.00 FUT8 (0.46) FUT8CHATUSP2APEX1ENPP3
SCHEMBL12954926 0.95 FUT8 (0.43) FUT8CHATUSP2APEX1ENPP3
SCHEMBL9270771 0.95 FUT8 (0.48) FUT8CHATUSP2APEX1ENPP3
SCHEMBL9740928 0.95 FUT8 (0.48) FUT8CHATUSP2APEX1ENPP3
SCHEMBL15363307 0.90 FUT8 (0.37) FUT8NT5EMEN1THRBKMT2A
SCHEMBL13881093 0.90 FUT8 (0.37) FUT8NT5EMEN1THRBKMT2A
SCHEMBL20314643 0.90 FUT8 (0.43) FUT8CHATUSP2APEX1ENPP3
SCHEMBL13880751 0.89 FUT8 (0.47) FUT8CHATUSP2APEX1ENPP3
SCHEMBL12172935 0.88 FUT8 (0.44) FUT8CHATUSP2APEX1ENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306600-A1 REACTIVE DYE COMPOSITION AND APPLICATION THEREOF Everlight Chemical Industrial Corporation (TW) 2024-01-17 — — EP disclosed
US-20160326384-A1 HIGH FIXATION INK COMPOSITION FOR DIGITAL TEXTILE PRINTING EVERLIGHT CHEMICAL INDUSTRIAL CORPORATION (TW) 2016-11-10 — — US disclosed
US-20160326384-A1 HIGH FIXATION INK COMPOSITION FOR DIGITAL TEXTILE PRINTING EVERLIGHT CHEMICAL INDUSTRIAL CORPORATION (TW) 2016-11-10 — — US disclosed
US-9403987-B2 Charged particles BASF SE (DE) 2016-08-02 — — US disclosed
US-8367823-B2 Colorants based N-halamines compositions and method of making and using BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-02-05 — — US disclosed
US-20120229884-A1 CHARGED PARTICLES BASF SE (DE) 2012-09-13 — — US disclosed
WO-2010149505-A2 CHARGED PARTICLES BASF SE (DE) 2010-12-29 — — WO disclosed
US-20100047426-A1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2010-02-25 — — US disclosed
US-20100047426-A1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2010-02-25 — — US disclosed
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION BASF SE (DE) 2010-02-04 — — US disclosed
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION BASF SE (DE) 2010-02-04 — — US disclosed
US-20090074825-A1 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074825-A1 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING TYR, MPO, NISCH FUT8 651/4885CHAT 218/4885USP2 1698/4885
US-20120229884-A1 CHARGED PARTICLES POLE3, POLD3, IPO4 FUT8 769/4885CHAT 1302/4885USP2 3518/4885
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION TAS2R13, TAS2R10, TAS2R16 FUT8 2375/4885CHAT 1197/4885USP2 4172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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