SCHEMBL416847

SCHEMBL416847

[C]1=C=CCc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29246 0.75
SCHEMBL976714 0.71 TSHR (0.31) TSHR
SCHEMBL4121654 0.67
SCHEMBL15466839 0.65 CA1 (0.37)
SCHEMBL8492495 0.65
SCHEMBL917202 0.64 MAOA (0.34)
SCHEMBL15154 0.62 TSHR (0.31) TSHR
SCHEMBL1848730 0.60
SCHEMBL876180 0.60 TSHR (0.33) TSHR
SCHEMBL11105969 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US claimed
EP-3008757-B1 OPTICAL DETECTOR AND METHOD FOR MANUFACTURING THE SAME BASF SE (DE) 2024-05-15 EP disclosed
US-11605790-B2 Monosubstituted diazabenzimidazole carbene metal complexes for use in organic light emitting diodes UDC IRELAND LIMITED (IE) 2023-03-14 US disclosed
EP-3126371-B1 METAL COMPLEXES, COMPRISING CARBENE LIGANDS HAVING AN O-SUBSTITUTED NON-CYCLOMETALATED ARYL GROUP AND THEIR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2021-11-10 EP disclosed
US-11125880-B2 Optical detector BASF SE (DE) 2021-09-21 US disclosed
US-11041718-B2 Detector for determining a position of at least one object BASF SE (DE) 2021-06-22 US disclosed
US-11031559-B2 Phenoxasiline based compounds for electronic application UDC IRELAND LIMITED (IE) 2021-06-08 US disclosed
EP-2936052-B1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2021-04-28 EP disclosed
EP-2165377-B1 ORGANIC LIGHT-EMITTING DIODES CONTAINING CARBENE TRANSITION METAL COMPLEX EMITTERS AND AT LEAST ONE COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S,S-DIOXIDES UDC IRELAND LTD (IE) 2021-04-28 EP disclosed
EP-3036558-B1 DETECTOR FOR DETERMINING A POSITION OF AT LEAST ONE OBJECT BASF SE (DE) 2020-12-16 EP disclosed
WO-2006074957-A1 SUBSTITUTED AMINOMETHYLENE SULPHONAMIDES, PRODUCTION AND USE THEREOF AS MEDICAMENTS SANOFI-AVENTIS (DE) 2006-07-20 WO disclosed
WO-2006056465-A1 PHENOTHIAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed
WO-2006018279-A2 ARYL-SUBSTITUTED POLYCYCLIC AMINES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2006-02-23 WO disclosed
WO-2006018280-A2 ARYL-SUBSTITUTED POLYCYCLIC AMINES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2006-02-23 WO disclosed
EP-1604988-A1 Pyridazinone derivatives, methods for producing them and their use as pharmaceuticals Sanofi-Aventis Deutschland GmbH (DE) 2005-12-14 EP disclosed
EP-1598348-A1 Novel pyridazinone derivatives as inhibitors of CDK2 Aventis Pharma Deutschland GmbH (DE) 2005-11-23 EP disclosed
US-20050176795-A1 Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments AVENTIS PHARMA DEUTSCHLAND GMBH 2005-08-11 US disclosed
US-20050176710-A1 Aryl-substituted heterocycles, process for their preparation and their use as medicaments AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-08-11 US disclosed
WO-2005070898-A1 SUBSTITUTED N-CYCLOHEXYL IMIDAZOLINONES HAVING AN MCH-MODULATORY EFFECT SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2005-08-04 WO disclosed
WO-2005070925-A1 ARYL SUBSTITUTED HETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2005-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050176710-A1 Aryl-substituted heterocycles, process for their preparation and their use as medicaments CYP11B1, CYP11B2, GPR119 TSHR 1013/4885
US-11605790-B2 Monosubstituted diazabenzimidazole carbene metal complexes for use in organic light emitting diodes DDT, OCIAD1, OCIAD2 TSHR 3463/4885
US-20050176795-A1 Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments CYP11B1, CYP11B2, GPR119 TSHR 3067/4885
US-11031559-B2 Phenoxasiline based compounds for electronic application PPOX, FZD7, OGFOD1 TSHR 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.