Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184603 | 0.74 | ALOX15 (0.56) | L3MBTL1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4184600 | 0.74 | ALOX15 (0.56) | L3MBTL1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4179985 | 0.74 | RAB9A (0.50) | L3MBTL1ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL4176051 | 0.74 | HPGD (0.46) | HPGDHSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL27725520 | 0.73 | L3MBTL1 (0.60) | L3MBTL1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4176813 | 0.72 | RAB9A (0.38) | L3MBTL1HPGDALDH1A1KDM4ERAB9A | |
| SCHEMBL5321616 | 0.71 | HPGD (0.69) | L3MBTL1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL249932 | 0.71 | HPGD (0.58) | L3MBTL1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL22861337 | 0.70 | SMN1; SMN2 (0.63) | L3MBTL1HPGDHSD17B10ALDH1A1GAA | |
| SCHEMBL12024781 | 0.68 | LMNA (0.62) | L3MBTL1HPGDHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143410-A1 | Isoxazolines for Controlling Invertebrate Pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| CN-101330828-A | Isoxazolines for controlling invertebrate pests | DU PONT (US) | 2008-12-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143410-A1 | Isoxazolines for Controlling Invertebrate Pests | CBR3, RTN3, HCN3 | L3MBTL1 727/4885HPGD 4021/4885HSD17B10 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.