Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510145 | 0.90 | HIF1A (0.64) | HIF1ACYP3A4TSHRBCHEACHE | |
| SCHEMBL11511619 | 0.90 | FFAR1 (0.61) | HIF1ACYP3A4TSHRFFAR1BCHE | |
| SCHEMBL11511829 | 0.89 | MEN1 (0.55) | HIF1ACYP3A4TSHRBCHEACHE | |
| SCHEMBL4699374 | 0.89 | HIF1A (0.77) | HIF1ACYP3A4TSHRKMT2AMEN1 | |
| SCHEMBL6690772 | 0.86 | HTT (0.57) | CYP3A4FFAR1KMT2AMEN1METAP2 | |
| SCHEMBL11511650 | 0.85 | HIF1A (0.54) | HIF1ACYP3A4TSHRBCHEACHE | |
| SCHEMBL11510198 | 0.84 | HTT (0.52) | HIF1AFFAR1KMT2AMEN1GAA | |
| SCHEMBL5452615 | 0.84 | MAOB (0.64) | HIF1ABCHEACHEKMT2AMEN1 | |
| SCHEMBL1966732 | 0.84 | NLRP3 (0.59) | HIF1AFFAR1BCHEACHEKMT2A | |
| SCHEMBL8085499 | 0.81 | L3MBTL1 (0.63) | HIF1ACYP3A4TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002044284-A1 | TRISAZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-06 | — | — | WO | claimed |
| JP-57190049-A | — | — | None | — | — | JP | disclosed |
| US-10961231-B2 | NTCP inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-03-30 | — | — | US | disclosed |
| US-20210040072-A1 | NTCP Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-02-11 | — | — | US | disclosed |
| CN-104277051-B | 4 aminothiophenes simultaneously [3,2 C] carboxylic acid derivates of pyridine 7 | 霍夫曼-拉罗奇有限公司 | 2017-06-09 | — | — | CN | disclosed |
| EP-1926737-B1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2017-03-15 | — | — | EP | disclosed |
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | CISTIM (BE) | 2016-04-28 | — | — | US | disclosed |
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | CISTIM (BE) | 2016-04-28 | — | — | US | disclosed |
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | CISTIM (BE) | 2016-04-28 | — | — | US | disclosed |
| EP-3004073-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | Université catholique de Louvain (BE) | 2016-04-13 | — | — | EP | disclosed |
| US-5484900-A | METALLIZED DYES FOR LEATHER, WOOL, SILK OR SYNTHETIC SUBSTRATES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |
| EP-0360014-B1 | Photosensitive material and image forming method using same | CANON KK (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5415974-A | Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye | CANON KABUSHIKI KAISHA (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0613928-A1 | 1:2 chromium complex dyes | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| EP-0360014-A1 | Photosensitive material and image forming method using same | CANON KABUSHIKI KAISHA (JP) | 1990-03-28 | — | — | EP | disclosed |
| JP-S57190049-A | FLUORAN COMPOUND, ITS PREPARATION, AND COLOR-DEVELOPING RECORDING MATERIAL CONTAINING THE SAME | YAMADA KAGAKU KOGYO KK | 1982-11-22 | — | — | JP | disclosed |
| US-4200753-A | Water-soluble fluorescing and lasing dyes | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1980-04-29 | — | — | US | disclosed |
| US-RE30199-E | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4003699-A | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL & CIE G.M.B.H. (DT) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040072-A1 | NTCP Inhibitors | HAVCR2, NPC1, HMGCR | HIF1A 1321/4885CYP3A4 739/4885TSHR 2808/4885 |
| US-20160115146-A1 | 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES | SLC16A3, SLC16A1, SLC16A8 | HIF1A 362/4885CYP3A4 141/4885TSHR 4637/4885 |
| US-10961231-B2 | NTCP inhibitors | HAVCR2, NPC1, HMGCR | HIF1A 1321/4885CYP3A4 739/4885TSHR 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.