Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 5/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.58 |
| ▸ | PFKFB2 | O60825 | 6/20 | 0.52 |
| ▸ | PFKFB1 | P16118 | 6/20 | 0.52 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | AS3MT | Q9HBK9 | 2/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498764 | 0.87 | AR (0.49) | MTNR1BMTNR1APFKFB2PFKFB1PFKFB3 | |
| SCHEMBL17536366 | 0.85 | MTNR1B (0.63) | MTNR1BMTNR1APFKFB2PFKFB1PFKFB3 | |
| SCHEMBL17536369 | 0.84 | MTNR1B (0.56) | MTNR1BMTNR1APFKFB2PFKFB1PFKFB3 | |
| SCHEMBL14447210 | 0.75 | MTNR1B (0.66) | MTNR1BMTNR1AMEN1ALDH1A1HPGD | |
| SCHEMBL22565006 | 0.74 | JUN (0.44) | MEN1LMNAKMT2APGRPLA2G7 | |
| SCHEMBL8144477 | 0.74 | MTNR1B (1.00) | MTNR1BMTNR1APGR | |
| SCHEMBL13720660 | 0.73 | GFER (0.48) | MTNR1BMTNR1APFKFB2PFKFB1PFKFB3 | |
| SCHEMBL8144897 | 0.73 | MTNR1B (0.75) | MTNR1BMTNR1AMEN1ALDH1A1KMT2A | |
| SCHEMBL17434515 | 0.73 | ALDH1A1 (0.54) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL8145133 | 0.73 | MTNR1B (0.74) | MTNR1BMTNR1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105349-A1 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2009-04-23 | — | — | US | claimed |
| US-20090105349-A1 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090105349-A1 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090105349-A1 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2009-04-23 | — | — | US | disclosed |
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105349-A1 | ANDROGEN MODULATORS | AR, NR5A1, SHBG | MTNR1B 126/4885MTNR1A 97/4885PFKFB2 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.