Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451858 | 0.83 | MEN1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL30042216 | 0.79 | MGAM (0.43) | — | |
| SCHEMBL995740 | 0.77 | — | — | |
| SCHEMBL821565 | 0.77 | — | — | |
| SCHEMBL9936149 | 0.76 | LMNA (0.52) | — | |
| SCHEMBL1921339 | 0.76 | — | — | |
| SCHEMBL4446358 | 0.75 | LMNA (0.59) | — | |
| SCHEMBL23754251 | 0.75 | CYP19A1 (0.52) | CYP19A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL5439857 | 0.75 | — | — | |
| SCHEMBL4453538 | 0.74 | LMNA (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-04-14 | — | — | US | disclosed |
| EP-2404891-B1 | PREPARATION METHOD OF ACYLBENZENES | DSM IP ASSETS BV (NL) | 2015-09-02 | — | — | EP | disclosed |
| CN-104725226-A | Preparation method of phenone | DSM IP ASSETS BV | 2015-06-24 | — | — | CN | disclosed |
| CN-102341362-B | Method for preparing acylbenzenes | DSM IP ASSETS BV | 2015-03-11 | — | — | CN | disclosed |
| WO-2014186631-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-11-20 | — | — | WO | disclosed |
| US-8642800-B2 | Preparation method of acylbenzenes | DSM IP ASSETS B.V. (NL) | 2014-02-04 | — | — | US | disclosed |
| CN-102341362-A | Method for preparing acylbenzenes | DSM IP ASSETS BV | 2012-02-01 | — | — | CN | disclosed |
| US-20120022284-A1 | PREPARATION METHOD OF ACYLBENZENES | DSM IP ASSETS B.V. (NL) | 2012-01-26 | — | — | US | disclosed |
| EP-2404891-A1 | PREPARATION METHOD OF ACYLBENZENES | DSM IP Assets B.V. (NL) | 2012-01-11 | — | — | EP | disclosed |
| US-20070207992-A1 | Geldanamycin derivatives and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-09-06 | — | — | US | disclosed |
| WO-2007098229-A2 | GELDANAMYCIN DERIVATIVES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2007-08-30 | — | — | WO | disclosed |
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20060205816-A1 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205816-A1 | Chiral lactones | HSD11B2, HSD11B1, HSD17B2 | CYP19A1 30/4885MMP1 4689/4885MMP2 2602/4885 |
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | ZFR, ZDHHC7, ORC3 | CYP19A1 371/4885MMP1 4137/4885MMP2 4530/4885 |
| US-20070207992-A1 | Geldanamycin derivatives and method of use thereof | HSP90AB2P, HSP90AB1, HSP90B1 | CYP19A1 3944/4885MMP1 3951/4885MMP2 963/4885 |
| US-20120022284-A1 | PREPARATION METHOD OF ACYLBENZENES | ACACB, SDHB, TET2 | CYP19A1 203/4885MMP1 4000/4885MMP2 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.