SCHEMBL4172174

SCHEMBL4172174

c1ccc(C23CC4CC(C2)CC(c2ccccc2)(C4)C3(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47
HSD11B1 P28845 2/20 0.41
MAOB P27338 9/20 0.39
MAOA P21397 6/20 0.39
P2RX7 Q99572 2/20 0.36
KDM1A O60341 3/20 0.35
ALOX5AP P20292 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL27599338 0.98 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Bromide SCHEMBL27584845 0.98 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Methylene Chloride SCHEMBL28265345 0.92 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8145335 0.81 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL28263951 0.79 ALDH1A1 (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9418910 0.79 MEN1 (0.49) MAOBP2RX7KDM1A
SCHEMBL9418932 0.79 LMNA (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1332710 0.79 CXCR3 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL27584838 0.76 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6939002 0.75 HSD11B1 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230769-B Preparation method of adamantyl organic porous polymer 齐鲁工业大学 2023-09-22 CN claimed
US-11535701-B2 Solvent-linked porous covalent organic polymers and method of preparing the same KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2022-12-27 US claimed
CN-114230769-A Preparation method of adamantyl organic porous polymer 齐鲁工业大学 2022-03-25 CN claimed
US-20200362094-A1 SOLVENT-LINKED POROUS COVALENT ORGANIC POLYMERS AND METHOD OF PREPARING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2020-11-19 US claimed
CN-106964323-B A kind of CO containing imine linkage2Adsorbent material and its preparation method and application 广东工业大学 2019-08-27 CN claimed
CN-109096539-A A kind of fire retardant and preparation method thereof, polycarbonate composite material and preparation method thereof 广东工业大学 2018-12-28 CN claimed
CN-109019751-A A kind of organic liquid waste adsorption treatment method 齐鲁工业大学 2018-12-18 CN claimed
CN-106279640-B Preparation method of nitro-functional group porous aromatic skeleton material 北京理工大学 2018-06-22 CN claimed
CN-106964323-A A kind of novel C O containing imine linkage2Sorbing material and its preparation method and application 广东工业大学 2017-07-21 CN claimed
US-6824890-B2 TOPOLOGICAL STRATEGY FOR DESIGNING AMORPHOUS MOLECULAR SOLIDS FOR FORMING THIN FILMS IN OPTOELECTRONIC DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-11-30 US claimed
US-20030055278-A1 Soluble tetrahedral compounds for use in electroluminescent devices NATIONAL SCIENCE FOUNDATION 2003-03-20 US claimed
WO-2001083410-A1 SOLUBLE TETRAHEDRAL COMPOUNDS FOR USE IN ELECTROLUMINESCENT DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-11-08 WO claimed
WO-2000003565-A1 AMORPHOUS MOLECULAR MATERIALS FOR OPTOELECTRONIC DEVICES AND PROCESS FOR PRODUCING THE SAME FED CORPORATION (US) 2000-01-20 WO claimed
CN-119529297-A Porous organic molecular framework material POM-TDTBA constructed by non-covalent pi accumulation, preparation method and application thereof 中国科学院福建物质结构研究所 2025-02-28 CN disclosed
US-20250025856-A1 NOVEL POROUS POLYMER COMPOSITIONS FOR THE SYNTHESIS OF MONOLITHIC BIMODAL MICROPOROUS/MACROPOROUS CARBON COMPOSITIONS USEFUL FOR SELECTIVE CO2 SEQUESTRATION ASPEN AEROGELS INC (US) 2025-01-23 US disclosed
EP-3328537-B1 A METHOD OF PREPARING A MICROPOROUS CARBON AND THE MICROPOROUS CARBON THEREBY OBTAINED SOL SPA (IT) 2025-01-01 EP disclosed
EP-1145160-A1 A GLOBAL METHOD FOR MAPPING PROPERTY SPACES AstraZeneca AB (SE) 2001-10-17 EP disclosed
WO-2000033218-A1 A GLOBAL METHOD FOR MAPPING PROPERTY SPACES ASTRAZENECA AB (SE) 2000-06-08 WO disclosed
WO-2000003565-A1 AMORPHOUS MOLECULAR MATERIALS FOR OPTOELECTRONIC DEVICES AND PROCESS FOR PRODUCING THE SAME FED CORPORATION (US) 2000-01-20 WO disclosed
US-5347063-A Method for direct arylation of diamondoids MOBIL OIL CORPORATION (US) 1994-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055278-A1 Soluble tetrahedral compounds for use in electroluminescent devices PAX3, EPCAM, PAXBP1 GRIN2D 539/4885GRIN3B 1694/4885GRIN1 2406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.