SCHEMBL8145335

SCHEMBL8145335

c1ccc(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc(C23CC4CC(C2)CC(c2ccccc2)(C4)C3(c2ccccc2)c2ccccc2)cc1.c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4172174 0.81 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Bromide SCHEMBL27599338 0.79 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Bromide SCHEMBL27584845 0.79 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Methylene Chloride SCHEMBL28265345 0.75 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24032697 0.65 MEN1 (0.45) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9418932 0.64 LMNA (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL28263951 0.64 ALDH1A1 (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1332710 0.64 CXCR3 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9418910 0.64 MEN1 (0.49)
SCHEMBL18175871 0.63 KIF11 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000003565-A1 AMORPHOUS MOLECULAR MATERIALS FOR OPTOELECTRONIC DEVICES AND PROCESS FOR PRODUCING THE SAME FED CORPORATION (US) 2000-01-20 WO disclosed