Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666319 | 0.80 | CYP19A1 (0.41) | CYP2C9MAOBGAAPOLB | |
| SCHEMBL26999420 | 0.74 | MAPK1 (0.47) | MAPK1CXCL12MAOB | |
| SCHEMBL4745736 | 0.72 | ALDH1A1 (0.48) | MAPK1PPARGCYP2C9CYP2C19NPSR1 | |
| SCHEMBL6147355 | 0.71 | RXRA (0.41) | PPARG | |
| SCHEMBL8768071 | 0.71 | CA2 (0.44) | MAPK1CYP1A2CYP2C9GAANPSR1 | |
| SCHEMBL3412742 | 0.71 | SLC6A4 (0.41) | MAPK1 | |
| SCHEMBL13223296 | 0.70 | TSHR (0.42) | PPARGPPARACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15330419 | 0.70 | PPARG (0.42) | PPARGPPARACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5309576 | 0.70 | TYR (0.41) | PPARGMAOB | |
| SCHEMBL9421466 | 0.67 | ALDH1A3 (0.44) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149444-A1 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149444-A1 | Benzylamine analogues | HTR4, DRD4, SLC6A4 | MAPK1 2703/4885PPARG 3434/4885PPARA 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.