SCHEMBL4176876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4182080	0.90	METAP2 (0.69)	CBFBMETAP2METAP1TRPV1RUNX1
	SCHEMBL4189664	0.86	CBFB (0.81)	CBFBDGAT1KCNH2NPBWR1METAP2
	SCHEMBL4179971	0.84	CBFB (0.67)	CBFBMETAP2METAP1RUNX1SCD
	SCHEMBL4186727	0.83	CBFB (0.55)	CBFB
	SCHEMBL4189141	0.83	TRPV1 (0.73)	CBFBDGAT1KCNH2NPBWR1TRPV1
	SCHEMBL4188605	0.82	CBFB (0.69)	CBFBDGAT1KCNH2NPBWR1METAP2
	SCHEMBL4811680	0.79	CBFB (0.85)	CBFBDGAT1KCNH2NPBWR1METAP2
	SCHEMBL15232048	0.77	NPBWR1 (0.53)	CBFBDGAT1KCNH2NPBWR1SOAT1
	SCHEMBL899088	0.77	NPBWR1 (0.56)	CBFBDGAT1KCNH2NPBWR1SOAT1
	SCHEMBL31593027	0.76	CBFB (0.64)	CBFBDGAT1KCNH2NPBWR1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.