Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13515990 | 0.92 | CYP1A2 (0.31) | CYP3A4CYP1A2CYP2C19MRGPRX4 | |
| SCHEMBL13516494 | 0.92 | CYP1A2 (0.31) | CYP3A4CYP1A2CYP2C19MRGPRX4 | |
| SCHEMBL299601 | 0.81 | ALDH1A1 (0.46) | CYP3A4CYP1A2CYP2C19MRGPRX4ALDH1A1 | |
| SCHEMBL21614495 | 0.81 | PGK1 (0.35) | CYP3A4CYP1A2CYP2C19SLC1A5PGK1 | |
| SCHEMBL13508303 | 0.81 | POLB (0.35) | CYP3A4ALDH1A1POLB | |
| SCHEMBL1000004 | 0.80 | CYP1A2 (0.31) | CYP3A4CYP1A2CYP2C19MRGPRX4 | |
| SCHEMBL1274350 | 0.79 | GAA (0.30) | — | |
| SCHEMBL9895270 | 0.79 | — | — | |
| SCHEMBL16702806 | 0.79 | SLC1A5 (0.34) | SLC1A5PGK1GRIA1CACNG8 | |
| SCHEMBL16703480 | 0.76 | SLC22A12 (0.34) | GRIA1CACNG8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048847-A1 | PROCESS FOR PREPARING SUBSTITUTED ANILINES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-02-17 | — | — | US | disclosed |
| EP-3898574-A1 | PROCESS FOR PREPARING SUBSTITUTED ANILINES | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-20210276958-A1 | METHOD FOR PRODUCING SUBSTITUTED N-ARYL PYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-09-09 | — | — | US | disclosed |
| US-10981888-B2 | Preparation method for tricyclic compounds | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-20 | — | — | US | disclosed |
| EP-3802496-A1 | METHOD FOR PRODUCING SUBSTITUTED N-ARYL PYRAZOLES | Bayer Aktiengesellschaft (DE) | 2021-04-14 | — | — | EP | disclosed |
| WO-2020126819-A1 | PROCESS FOR PREPARING SUBSTITUTED ANILINES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-20190315707-A1 | PREPARATION METHOD FOR TRICYCLIC COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-17 | — | — | US | disclosed |
| EP-3551616-A1 | METHOD FOR PRODUCING 5-(1-PHENYL-1H-PYRAZOLE-4-YL)-NICOTINAMIDE DERIVATIVES AND SIMILAR COMPOUNDS WITHOUT ISOLATING OR PURIFYING THE PHENYLHYDRAZINE INTERMEDIATE | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-16 | — | — | EP | disclosed |
| US-10150737-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-12-11 | — | — | US | disclosed |
| WO-2018104214-A1 | METHOD FOR PRODUCING 5-(1-PHENYL-1H-PYRAZOLE-4-YL)-NICOTINAMIDE DERIVATIVES AND SIMILAR COMPOUNDS WITHOUT ISOLATING OR PURIFYING THE PHENYLHYDRAZINE INTERMEDIATE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-14 | — | — | WO | disclosed |
| EP-3066080-A1 | SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS | Bayer CropScience Aktiengesellschaft (DE) | 2016-09-14 | — | — | EP | disclosed |
| EP-3066079-A1 | SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES | Bayer CropScience Aktiengesellschaft (DE) | 2016-09-14 | — | — | EP | disclosed |
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| WO-2015067647-A1 | SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067646-A1 | SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| US-8822691-B2 | Pesticidal carboxamides | BAYER CROPSCIENCE AG (DE) | 2014-09-02 | — | — | US | disclosed |
| US-20120277185-A1 | Pesticidal Carboxamides | BAYER CROPSCIENDE AG (DE) | 2012-11-01 | — | — | US | disclosed |
| US-20120149910-A1 | Pesticidal Carboxamides | BAYER CROPSCIENCE AG (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-1916236-A1 | AMIDE DERIVATIVE, PESTICIDE CONTAINING SUCH COMPOUND AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277185-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | CYP3A4 548/4885CYP1A2 309/4885CYP2C19 537/4885 |
| US-10981888-B2 | Preparation method for tricyclic compounds | CYP4B1, CYP3A4, CYP1A1 | CYP3A4 2/4885CYP1A2 5/4885CYP2C19 12/4885 |
| US-20190315707-A1 | PREPARATION METHOD FOR TRICYCLIC COMPOUNDS | CYP4B1, CYP3A4, CYP1A1 | CYP3A4 2/4885CYP1A2 5/4885CYP2C19 12/4885 |
| US-20220048847-A1 | PROCESS FOR PREPARING SUBSTITUTED ANILINES | CYP1A2, CYP1A1, CYP1B1 | CYP3A4 4/4885CYP1A2 1/4885CYP2C19 9/4885 |
| US-20210276958-A1 | METHOD FOR PRODUCING SUBSTITUTED N-ARYL PYRAZOLES | CYP4B1, CYP1B1, CYP1A2 | CYP3A4 4/4885CYP1A2 3/4885CYP2C19 11/4885 |
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | CYP2E1, GSTA1, CYP2S1 | CYP3A4 19/4885CYP1A2 6/4885CYP2C19 141/4885 |
| US-10150737-B2 | Compounds for controlling arthropods | SERPINB6, CYP4X1, C1S | CYP3A4 194/4885CYP1A2 114/4885CYP2C19 734/4885 |
| US-20120149910-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | CYP3A4 772/4885CYP1A2 338/4885CYP2C19 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.