SCHEMBL4184039

SCHEMBL4184039

CCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.72
ACE P12821 4/20 0.70
POLB P06746 3/20 0.67
ITGB2 P05107 2/20 0.67
ICAM1 P05362 2/20 0.67
ITGAL P20701 2/20 0.67
P2RY14 Q15391 1/20 0.67
TP53 P04637 1/20 0.67
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
MAPT P10636 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
KDM4E B2RXH2 1/20 0.65
HTT P42858 1/20 0.65
ECE1 P42892 4/20 0.65
ERAP2 Q6P179 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195982 1.00 ALOX15 (0.72) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL4184041 1.00 ALOX15 (0.72) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL11382215 0.91 ALOX15 (0.70) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL11382213 0.91 ALOX15 (0.70) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL28401652 0.90 ALOX15 (0.69) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL28401650 0.90 ALOX15 (0.69) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL23380932 0.90 ALOX15 (0.61) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL14300977 0.90 ALOX15 (0.61) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL27552844 0.89 ALOX15 (0.74) ALOX15ACEPOLBITGB2ICAM1
SCHEMBL27552842 0.89 ALOX15 (0.74) ALOX15ACEPOLBITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339370-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS AVANTOR PERFORMANCE MATERIALS, LLC (US) 2025-11-06 US claimed
EP-4319795-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS Avantor Performance Materials, LLC (US) 2024-02-14 EP claimed
CN-117355321-A Performance enhancing excipients and methods for reducing viscosity and improving stability of biological agents 安万托特性材料股份有限公司 2024-01-05 CN claimed
US-20230248682-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID STEMDR INC. (KR) 2023-08-10 US claimed
WO-2022217021-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS AVANTOR PERFORMANCE MATERIALS, LLC (US) 2022-10-13 WO claimed
US-20220233485-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID STEMDR INC. (KR) 2022-07-28 US claimed
US-20090186853-A1 COMPOSITIONS COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF YU RUEY J 2009-07-23 US claimed
EP-1865953-A4 COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF YU RUEY J (US) 2008-04-30 EP claimed
EP-1865953-A2 COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF Yu, Ruey J., Dr. (US) 2007-12-19 EP claimed
WO-2006101940-A2 COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF YU, RUEY, J. (US) 2006-09-28 WO claimed
US-20060211754-A1 Compositions comprising N-propanoyl derivatives of amino acids, aminocarbohydrates and derivatives thereof YU RUEY J 2006-09-21 US claimed
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US claimed
WO-2005055947-A2 ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS YU RUEY J (US) 2005-06-23 WO claimed
US-20250339370-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS AVANTOR PERFORMANCE MATERIALS, LLC (US) 2025-11-06 US disclosed
US-20250339370-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS AVANTOR PERFORMANCE MATERIALS, LLC (US) 2025-11-06 US disclosed
US-12370161-B2 Composition for treating atopy or pruritus comprising N-acetyl or N-acyl amino acid STEMDR INC. (KR) 2025-07-29 US disclosed
US-20060211754-A1 Compositions comprising N-propanoyl derivatives of amino acids, aminocarbohydrates and derivatives thereof YU RUEY J 2006-09-21 US disclosed
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US disclosed
WO-2005055947-A2 ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS YU RUEY J (US) 2005-06-23 WO disclosed
US-4283337-A Process for the purification of tryptophane and derivatives of tryptophane DEUTSCHE GOLD UND- SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220233485-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID AADAT, NAT1, AANAT ALOX15 120/4885ACE 1181/4885POLB 3182/4885
US-20250339370-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS AADAT, KYNU, PNISR ALOX15 2713/4885ACE 1279/4885POLB 1203/4885
US-20230248682-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID AADAT, NAT1, AANAT ALOX15 120/4885ACE 1181/4885POLB 3182/4885
US-12370161-B2 Composition for treating atopy or pruritus comprising N-acetyl or N-acyl amino acid AADAT, NAT1, AANAT ALOX15 120/4885ACE 1181/4885POLB 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.