Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631953 | 0.84 | RORC (0.46) | POLBALDH1A1NPSR1TSHRHSD17B10 | |
| SCHEMBL13631949 | 0.82 | RORC (0.48) | POLBALDH1A1NPSR1NR1I2TSHR | |
| SCHEMBL16894172 | 0.81 | POLB (0.70) | POLBALDH1A1NPSR1NR1I2TSHR | |
| SCHEMBL13631950 | 0.81 | HCRTR2 (0.42) | TSHRHSD17B10HCRTR2HSD17B1HSD17B2 | |
| SCHEMBL3462930 | 0.80 | HCRTR2 (0.53) | POLBALDH1A1NPSR1NR1I2TSHR | |
| SCHEMBL3460857 | 0.78 | HCRTR2 (0.48) | POLBALDH1A1NPSR1MAPTHCRTR2 | |
| SCHEMBL14018611 | 0.77 | HSD17B1 (0.62) | HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL3461871 | 0.77 | HCRTR2 (0.50) | POLBALDH1A1NPSR1PKMMAPT | |
| SCHEMBL4189643 | 0.77 | KMT2A (0.54) | POLBALDH1A1NPSR1PKMHSD17B10 | |
| SCHEMBL4877336 | 0.76 | TDP1 (0.62) | ALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286713-A9 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2009-11-19 | — | — | US | disclosed |
| US-20090286713-A9 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2009-11-19 | — | — | US | disclosed |
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
| US-20080255028-A1 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2008-10-16 | — | — | US | disclosed |
| US-20080255028-A1 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2008-10-16 | — | — | US | disclosed |
| EP-1924554-A1 | SULPHONAMIDE DERIVATIVES | Biotie Therapies Corp. (FI) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007034035-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | POLB 4549/4885ALDH1A1 872/4885NPSR1 118/4885 |
| US-20080255028-A1 | Collagen Receptor I-Domain Binding Modulators | COL14A1, COL2A1, COL1A1 | POLB 3530/4885ALDH1A1 2678/4885NPSR1 585/4885 |
| US-20090286713-A9 | Collagen Receptor I-Domain Binding Modulators | COL14A1, COL2A1, COL1A1 | POLB 3530/4885ALDH1A1 2678/4885NPSR1 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.