Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018611 | 0.83 | HSD17B1 (0.62) | HSD17B1HSD17B2NR1H3HSD17B10TDP1 | |
| SCHEMBL13631953 | 0.78 | RORC (0.46) | KMT2AHSD17B1HSD17B2POLBNR1H3 | |
| SCHEMBL4186586 | 0.77 | POLB (0.59) | HSD17B1HSD17B2POLBHSD17B10ALDH1A1 | |
| SCHEMBL13631950 | 0.77 | HCRTR2 (0.42) | KMT2AHSD17B1HSD17B2MEN1NR1H3 | |
| SCHEMBL4877336 | 0.76 | TDP1 (0.62) | LMNAALDH1A1MAPTPKMTDP1 | |
| SCHEMBL715206 | 0.74 | HSD17B1 (0.40) | KMT2AHSD17B1HSD17B2PNPLA2HDAC6 | |
| SCHEMBL715207 | 0.74 | PNPLA2 (0.42) | KMT2AHSD17B1HSD17B2MEN1PNPLA2 | |
| SCHEMBL4183469 | 0.74 | HSD17B1 (0.57) | KMT2AHSD17B1HSD17B2MEN1NR1H3 | |
| SCHEMBL13631949 | 0.74 | RORC (0.48) | KMT2AHSD17B1HSD17B2POLBNR1H3 | |
| SCHEMBL3461784 | 0.73 | HSD17B1 (0.59) | HSD17B1HSD17B2NR1H3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286713-A9 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2009-11-19 | — | — | US | disclosed |
| US-20090286713-A9 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2009-11-19 | — | — | US | disclosed |
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
| US-20080255028-A1 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2008-10-16 | — | — | US | disclosed |
| US-20080255028-A1 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | KMT2A 2643/4885HSD17B1 2903/4885HSD17B2 2702/4885 |
| US-20080255028-A1 | Collagen Receptor I-Domain Binding Modulators | COL14A1, COL2A1, COL1A1 | KMT2A 1540/4885HSD17B1 3438/4885HSD17B2 3494/4885 |
| US-20090286713-A9 | Collagen Receptor I-Domain Binding Modulators | COL14A1, COL2A1, COL1A1 | KMT2A 1540/4885HSD17B1 3438/4885HSD17B2 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.