SCHEMBL418767

SCHEMBL418767

CC1(C)OB(c2ccc(C(F)(F)F)cc2)OC1(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.56
LIPG Q9Y5X9 12/20 0.56
F11 P03951 3/20 0.48
F2 P00734 2/20 0.48
PRSS1 P07477 2/20 0.48
PRSS2 P07478 2/20 0.48
PRSS3 P35030 2/20 0.48
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA9 Q16790 3/20 0.45
CA12 O43570 1/20 0.45
CA3 P07451 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
ESR2 Q92731 1/20 0.41
P4HB P07237 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19830999 0.94 LIPG (0.66) LPLLIPGF11F2PRSS1
Cyclopentane SCHEMBL28610823 0.94 LPL (0.51) LPLLIPGF11F2PRSS1
SCHEMBL805968 0.90 CA1 (0.49) LPLLIPGF11F2PRSS1
SCHEMBL15803122 0.90 LPL (0.47) LPLLIPGF11F2PRSS1
SCHEMBL12630073 0.86 LPL (0.55) LPLLIPGF11F2PRSS1
SCHEMBL4290411 0.85 LPL (0.53) LPLLIPGF11F2PRSS1
SCHEMBL21370131 0.85 LPL (0.53) LPLLIPGF11F2PRSS1
SCHEMBL18615134 0.85 LPL (0.53) LPLLIPGF11F2PRSS1
SCHEMBL19834910 0.83 LPL (0.57) LPLLIPGF11F2PRSS1
SCHEMBL24871312 0.83 LPL (0.51) LPLLIPGF11F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108064426-B Electrolyte formulation for lithium ion batteries 野猫技术开发公司 2021-07-30 CN claimed
US-10547083-B2 Electrolyte formulations for lithium ion batteries WILDCAT DISCOVERY TECHNOLOGIES, INC. (US) 2020-01-28 US claimed
US-20160372791-A1 ELECTROLYTE FORMULATIONS FOR LITHIUM ION BATTERIES JOHNSON CONTROLS TECHNOLOGY COMPANY (US) 2016-12-22 US claimed
US-20160372790-A1 ELECTROLYTE FORMULATIONS FOR LITHIUM ION BATTERIES JOHNSON CONTROLS TECHNOLOGY COMPANY (US) 2016-12-22 US claimed
US-6559310-B2 Reacting a halogen aromatic derivative at a coupling position with a diboron derivative in the presence of a Group VIII metal catalyst and a suitable base for covalently coupling organic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-05-06 US claimed
US-20020193604-A1 Aryl borates COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2002-12-19 US claimed
US-20020032339-A1 ARYL BORATES BORON MOLECULAR LIMITED (AU) 2002-03-14 US claimed
EP-4271674-B9 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-03-11 EP disclosed
US-12534458-B2 Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors MERCK SHARP & DOHME LLC (US) 2026-01-27 US disclosed
EP-4271674-B3 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
US-20250312352-A1 GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. 2025-10-09 US disclosed
US-20250230168-A1 AZASPIRO WRN INHIBITORS GILEAD SCIENCES, INC. 2025-07-17 US disclosed
WO-2025137640-A1 AZASPIRO WRN INHIBITORS GILEAD SCIENCES, INC. (US) 2025-06-26 WO disclosed
EP-1127060-B8 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2005-01-05 EP disclosed
US-20040133028-A1 Hydroboronation process COMMONWEALTH SCIENTIFIC 2004-07-08 US disclosed
EP-1127060-B1 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2004-04-07 EP disclosed
US-6680401-B1 BORON COMPOUNDS SUCH AS 4-(METHOXYMETHYL)-1,3,2-DIOXABOROLANE, USED AS COUPLERS OR CHEMICAL INTERMEDIATES FOR DRUGS, PESTICIDES OR IN COMBINATORIAL CHEMISTRY COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-01-20 US disclosed
EP-1127060-A4 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2002-08-21 EP disclosed
EP-1127060-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2001-08-29 EP disclosed
WO-2000027853-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534458-B2 Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors CHRNA6, CHRNA7, CHRNA5 LPL 1210/4885LIPG 3036/4885F11 4840/4885
US-20250230168-A1 AZASPIRO WRN INHIBITORS WRN, RECQL, BLM LPL 1985/4885LIPG 2901/4885F11 3401/4885
US-20250312352-A1 GLP-1R MODULATING COMPOUNDS GLP1R, GIPR, GPR119 LPL 99/4885LIPG 173/4885F11 4095/4885
US-20020193604-A1 Aryl borates BRD4, ABL1, BRD3 LPL 4181/4885LIPG 4621/4885F11 2756/4885
US-20040133028-A1 Hydroboronation process ALKBH3, HPD, HVCN1 LPL 4659/4885LIPG 4522/4885F11 2087/4885
US-20020032339-A1 ARYL BORATES TBCB, HAT1, UBE2B LPL 4584/4885LIPG 4847/4885F11 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.