SCHEMBL4188731

SCHEMBL4188731

CC(Nc1ccc(NC(C)N(C)C)c2c1C(=O)c1c(NC(C)N(C)C)ccc(NC(C)N(C)C)c1C2=O)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4197844 0.98 TERT (0.31) MALT1
SCHEMBL8789326 0.81 MAOA (0.45)
SCHEMBL18984702 0.78 IDO1 (0.41) MALT1POLB
SCHEMBL9619896 0.68 IDO1 (0.34) MALT1
SCHEMBL11805185 0.68 IDO1 (0.50) POLB
SCHEMBL29351322 0.67 MEN1 (0.52) MALT1POLB
SCHEMBL7906174 0.67 MDM4 (0.44) POLB
SCHEMBL30039621 0.67 MEN1 (0.52) MALT1POLB
SCHEMBL92040 0.67 MEN1 (0.52) MALT1POLB
SCHEMBL9706115 0.65 MAPT (0.41) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420861-B2 Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone ISHMAEL D RICHARD (US) 2013-04-16 US disclosed
US-20090156807-A1 Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone ISHMAEL D RICHARD 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156807-A1 Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone CASP4, CASP8, CASP1 MALT1 178/4885POLB 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.