Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4197846 | 0.98 | MALT1 (0.47) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL4189278 | 0.91 | NQO1 (0.43) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL4200297 | 0.91 | NQO1 (0.43) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL4200289 | 0.91 | NPSR1 (0.44) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL4198000 | 0.91 | SMN1; SMN2 (0.53) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL4196694 | 0.91 | SMN1; SMN2 (0.53) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL3418628 | 0.90 | THRB (0.45) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL3418071 | 0.90 | CYP19A1 (0.62) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL11277491 | 0.90 | CYP19A1 (0.62) | MALT1NQO1TOP2BALDH1A1NPSR1 | |
| SCHEMBL11522777 | 0.90 | CYP19A1 (0.62) | MALT1NQO1TOP2BALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420861-B2 | Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD (US) | 2013-04-16 | — | — | US | claimed |
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | claimed |
| US-8420861-B2 | Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420861-B2 | Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420861-B2 | Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD (US) | 2013-04-16 | — | — | US | disclosed |
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | disclosed |
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | disclosed |
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | CASP4, CASP8, CASP1 | MALT1 178/4885NQO1 957/4885TOP2B 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.