Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188735 | 0.85 | GLA (0.38) | GLAALDH1A1KMT2AMEN1GFER | |
| SCHEMBL2209548 | 0.75 | HRH4 (0.38) | GLAALDH1A1KMT2AMEN1GFER | |
| SCHEMBL2418127 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL2418209 | 0.74 | MAPT (0.54) | ALDH1A1KMT2AMEN1GFERLMNA | |
| SCHEMBL2418698 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1GFERLMNA | |
| SCHEMBL2412829 | 0.73 | SSTR3 (0.40) | KMT2A | |
| SCHEMBL2417712 | 0.72 | NPC1 (0.46) | KMT2AMEN1LMNAHTT | |
| SCHEMBL15231529 | 0.70 | ALOX15 (0.41) | ALDH1A1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL2962428 | 0.69 | EGFR (0.39) | GLAALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL2420011 | 0.69 | LMNA (0.39) | ALDH1A1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071604-B2 | Thio-substituted arylmethanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2011-12-06 | — | — | US | disclosed |
| US-20090018143-A1 | Thio-substituted arylmethanesulfinyl derivatives | CEPHALON, INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-7297817-B2 | Thio-substituted arylmethanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2007-11-20 | — | — | US | disclosed |
| US-20050256133-A1 | Thio-substituted arylmethanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2005-11-17 | — | — | US | disclosed |
| EP-1586560-A1 | Thio-substituted arylmethanesulfinyl derivatives | CEPHALON, INC. (US) | 2005-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256133-A1 | Thio-substituted arylmethanesulfinyl derivatives | HTR1A, SLC6A3, HTR3B | GLA 4156/4885ALDH1A1 1617/4885KMT2A 948/4885 |
| US-20090018143-A1 | Thio-substituted arylmethanesulfinyl derivatives | HTR1A, SLC6A3, HTR3B | GLA 4156/4885ALDH1A1 1617/4885KMT2A 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.