Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | NSD2 | O96028 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4200289 | 0.82 | NPSR1 (0.44) | NQO1CYP19A1MEN1BLMKMT2A | |
| SCHEMBL4192991 | 0.76 | CYP19A1 (0.44) | CYP19A1MEN1BLMKMT2ALMNA | |
| SCHEMBL18984670 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2ALMNAMAPK1TDP1 | |
| SCHEMBL13800043 | 0.72 | NPSR1 (0.42) | NQO1CYP19A1MEN1BLMKMT2A | |
| SCHEMBL4188736 | 0.72 | MALT1 (0.49) | NQO1CYP19A1MEN1BLMKMT2A | |
| Hydrochloric Acid SCHEMBL4197846 | 0.70 | MALT1 (0.47) | NQO1CYP19A1MEN1BLMKMT2A | |
| SCHEMBL14409248 | 0.66 | NQO1 (0.52) | NQO1CYP19A1MEN1BLMKMT2A | |
| SCHEMBL16602198 | 0.66 | CYP19A1 (0.56) | CYP19A1MEN1BLMKMT2ALMNA | |
| SCHEMBL4196694 | 0.66 | SMN1; SMN2 (0.53) | NQO1CYP19A1MEN1BLMKMT2A | |
| SCHEMBL4189278 | 0.66 | NQO1 (0.43) | NQO1CYP19A1MEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420861-B2 | Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD (US) | 2013-04-16 | — | — | US | disclosed |
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | CASP4, CASP8, CASP1 | NQO1 957/4885CYP19A1 2871/4885MEN1 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.