Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190688 | 1.00 | EPHX2 (0.56) | EPHX2FDPSKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25940376 | 0.85 | KDM4E (0.50) | EPHX2FDPSKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25943492 | 0.84 | TTR (0.48) | EPHX2FDPSKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23134789 | 0.82 | NFE2L2 (0.46) | EPHX2FDPSKDM4EALDH1A1MAPT | |
| SCHEMBL15210430 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2GAANFE2L2 | |
| SCHEMBL20551560 | 0.80 | P4HB (0.63) | EPHX2FDPSKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20551559 | 0.80 | P4HB (0.63) | EPHX2FDPSKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL66903 | 0.79 | FDPS (0.53) | EPHX2FDPSKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16320889 | 0.79 | ALDH1A1 (0.54) | FDPSKDM4EALDH1A1SMN1; SMN2MAPT | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411956 | 0.77 | FDPS (0.80) | EPHX2FDPSKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239865-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | PFIZER PRODUCTS INC. | 2009-09-24 | — | — | US | disclosed |
| EP-1817297-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | Pfizer Products Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056854-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239865-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | APOB, LDLR, CETP | EPHX2 1276/4885FDPS 1247/4885KDM4E 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.