SCHEMBL4194601

SCHEMBL4194601

SCCC[SiH2]C(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
HTR2A P28223 5/20 0.34
HRH1 P35367 5/20 0.34
TDP1 Q9NUW8 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
FOLH1 Q04609 1/20 0.33
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
MTOR P42345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4074158 0.79 TSHR (0.36) HTR2AHRH1TAAR1MTORRAB9A
SCHEMBL4660217 0.79 ALDH1A1 (0.40) HTR2AHRH1TDP1TAAR1
SCHEMBL3454935 0.74 TRPA1 (0.38) HTR2AHRH1TDP1TAAR1MTOR
SCHEMBL1270652 0.72 TAAR1 (0.42) HTR2AHRH1TAAR1MTORRAB9A
SCHEMBL4661596 0.71 HTT (0.32) HTR2AHRH1
SCHEMBL22551517 0.71 SCN1A (0.37) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9120332 0.70 HRH1 (0.62) HTR2AHRH1TDP1TAAR1FOLH1
SCHEMBL7935090 0.69 LMNA (0.39) HTR2AHRH1TAAR1MTORRAB9A
SCHEMBL2118480 0.69 TAAR1 (0.39) HTR2AHRH1TAAR1MTORRAB9A
SCHEMBL1645203 0.69 TSHR (0.42) HTR2AHRH1TAAR1MTORRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6507049-B1 Encapsulants for solid state devices GENERAL ELECTRIC COMPANY 2003-01-14 US claimed
WO-2002019440-A1 ENCAPSULANTS FOR SOLID STATE DEVICES GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO claimed
US-5145889-A For light-emitting diodes KABUSHIKI KAISHA TOSHIBA (JP) 1992-09-08 US claimed
US-20090121251-A1 Siloxane-hydantoin copolymer, optoelectronic device encapsulated therewith and method LUMINATION LLC 2009-05-14 US disclosed
US-20080160317-A1 Optoelectronic device GELCORE LLC 2008-07-03 US disclosed
US-20080001140-A1 Optoelectronic device GELCORE LLC 2008-01-03 US disclosed
US-20070299162-A1 Light emitting semiconductor and encapsulant is made from nano-functionalized zirconia; silicone epoxy, epoxy isocyanurate and succinic anhydride, dodecenylsuccinic anhydride, phthalic anhydride curing agent; ancillary curing catalyst, cure modifier, coupling agent, UV, thermal stabilizer GELCORE LLC 2007-12-27 US disclosed
US-20070295983-A1 Optoelectronic device GELCORE LLC 2007-12-27 US disclosed
US-20070295956-A1 Optoelectronic device GELCORE LLC 2007-12-27 US disclosed
EP-1408087-B1 Epoxy-polysiloxane resin compositions, solid state devices encapsulated therewith and method GEN ELECTRIC (US) 2007-10-10 EP disclosed
US-7144763-B2 light emitting diode; curable silicone with pendant epoxy groups, a hydroxyl-containing compound or silicone, anhydride curing agent, ancillary curing catalyst; radiation transparent, UV stability, clear; packaging GENERAL ELECTRIC COMPANY (US) 2006-12-05 US disclosed
US-6617400-B2 Free of halogen, and contains at least one cure modifier, and, optionally at least one ancillary curing catalyst; for encapsulating a solid state device GENERAL ELECTRIC COMPANY 2003-09-09 US disclosed
US-20030071366-A1 For encapsulating a solid state device, such as a light emitting diode GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
US-20030071368-A1 Epoxy resin compositions, solid state devices encapsulated therewith and method GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
US-20030071367-A1 Epoxy resin compositions, solid state devices encapsulated therewith and method GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
EP-1285938-A1 Epoxy resin encapsulation compositions GENERAL ELECTRIC COMPANY (US) 2003-02-26 EP disclosed
EP-1285939-A1 Epoxy resin compositions and solid state devices encapsulated therewith GENERAL ELECTRIC COMPANY (US) 2003-02-26 EP disclosed
US-6507049-B1 Encapsulants for solid state devices GENERAL ELECTRIC COMPANY 2003-01-14 US disclosed
WO-2002019440-A1 ENCAPSULANTS FOR SOLID STATE DEVICES GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO disclosed
US-5145889-A For light-emitting diodes KABUSHIKI KAISHA TOSHIBA (JP) 1992-09-08 US disclosed