Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454935 | 0.87 | TRPA1 (0.38) | ALDH1A1LMNAHSD17B10TRPA1HTR2A | |
| SCHEMBL27842300 | 0.81 | HRH1 (0.54) | HTR2ATAAR1HRH1CYP2D6 | |
| SCHEMBL4074158 | 0.79 | TSHR (0.36) | HTR2ATAAR1HRH1 | |
| SCHEMBL4194601 | 0.79 | HDAC3 (0.35) | HTR2ATDP1TAAR1HRH1 | |
| SCHEMBL7935090 | 0.78 | LMNA (0.39) | LMNATRPA1HTR2AKDM4EL3MBTL1 | |
| SCHEMBL1270652 | 0.72 | TAAR1 (0.42) | LMNAHTR2AKDM4EL3MBTL1TAAR1 | |
| SCHEMBL4661596 | 0.71 | HTT (0.32) | ALDH1A1LMNAHTR2AKDM4EHRH1 | |
| SCHEMBL6914191 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ECYP2D6SRC | |
| SCHEMBL5596219 | 0.71 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10TRPA1CCR3 | |
| SCHEMBL8542670 | 0.69 | ESR1 (0.45) | ALDH1A1KDM4EL3MBTL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444239-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB (US) | 2008-12-24 | — | — | EP | disclosed |
| US-7132494-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2006-11-07 | — | — | US | disclosed |
| US-6881809-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2005-04-19 | — | — | US | disclosed |
| CN-1582289-A | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB (US) | 2005-02-16 | — | — | CN | disclosed |
| US-6846897-B2 | High refractive index aromatic-based silyl monomers | BAUSCH AND LOMB, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040230023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-11-18 | — | — | US | disclosed |
| US-20040215156-A1 | High refractive index aromatic-based silyl monomers | SOLTA MEDICAL, INC. | 2004-10-28 | — | — | US | disclosed |
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C | 2004-10-28 | — | — | US | disclosed |
| US-20040210023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-10-21 | — | — | US | disclosed |
| EP-1444239-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-11 | — | — | EP | disclosed |
| US-6762271-B2 | INTRAOCULAR LENSES, CONTACT LENSES AND CORNEAL INLAYS | BAUSCH & LOMB INCORPORATED | 2004-07-13 | — | — | US | disclosed |
| US-20030105255-A1 | High refractive index aromatic-based silyl monomers | BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC. (CA) | 2003-06-05 | — | — | US | disclosed |
| WO-2003040152-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SMAD2, SMAD3, FHIT | ALDH1A1 3491/4885LMNA 1150/4885HSD17B10 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.