SCHEMBL4198151

SCHEMBL4198151

C=C(C)C(=O)OC(COc1cccc(-c2ccccc2)c1)COc1ccccc1OCC(COc1cccc(-c2ccccc2)c1)OC(=O)C(=C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.41
PTGER4 P35408 1/20 0.40
FFAR1 O14842 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
NR4A2 P43354 1/20 0.38
GGPS1 O95749 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197933 0.94 RXRA (0.43) RXRARXRBMRGPRX4PTGER4FFAR1
SCHEMBL4184755 0.94 RXRA (0.48) RXRARXRBMRGPRX4PTGER4FFAR1
SCHEMBL4188685 0.93 RXRA (0.47) RXRARXRBMRGPRX4PTGER4FFAR1
SCHEMBL4198139 0.92 RXRA (0.49) RXRARXRBMRGPRX4FFAR1PRMT5
SCHEMBL4202644 0.90 L3MBTL1 (0.44) RXRARXRBFFAR1
SCHEMBL4204184 0.89 MAPT (0.46) HDAC1HDAC2
SCHEMBL4197809 0.88 L3MBTL1 (0.48) RXRARXRB
SCHEMBL4184734 0.88 MAPT (0.45) RXRARXRBFFAR1
SCHEMBL4202672 0.86 RXRA (0.42) RXRARXRBMRGPRX4PTGER4FFAR1
SCHEMBL11957216 0.86 MTNR1A (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 RXRA 360/4885RXRB 538/4885MRGPRX4 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.