Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196298 | 0.90 | ALDH1A1 (0.46) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27863585 | 0.82 | GAA (0.52) | ALOX15ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4198230 | 0.82 | ALOX15 (0.63) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4199011 | 0.80 | NPC1 (0.53) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4195751 | 0.79 | MEN1 (0.53) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4198299 | 0.78 | KCNMA1 (0.59) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL4293229 | 0.75 | KDM4E (0.48) | ALOX15MAOBALDH1A1KDM4EGAA | |
| SCHEMBL13102688 | 0.75 | KCNMA1 (0.60) | ALOX15ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL404789 | 0.75 | HPGD (0.47) | ALOX15ALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL6177644 | 0.74 | KDM4E (0.57) | ALOX15ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX5, ALOX15B | ALOX15 1/4885CYP1A2 32/4885CYP3A4 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.