Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195751 | 0.88 | MEN1 (0.53) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4186735 | 0.85 | ALOX15 (0.65) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4199011 | 0.85 | NPC1 (0.53) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4205361 | 0.85 | RAB9A (0.56) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4188965 | 0.84 | MEN1 (0.45) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4198299 | 0.84 | KCNMA1 (0.59) | NPC1RAB9AKDM4EHPGDPOLB | |
| SCHEMBL4198306 | 0.82 | ALOX15 (0.44) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4196298 | 0.79 | ALDH1A1 (0.46) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4253110 | 0.79 | ALOX15 (0.68) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4748938 | 0.78 | CYP1A2 (0.58) | ALOX15CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX5, ALOX15B | ALOX15 1/4885CYP1A2 32/4885CYP3A4 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.