Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | FGR | P09769 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193002 | 0.88 | THRB (0.33) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL30102545 | 0.87 | MAPT (0.64) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL30102541 | 0.87 | MAPT (0.64) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL30039621 | 0.84 | MEN1 (0.52) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL92040 | 0.84 | MEN1 (0.52) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL29351322 | 0.84 | MEN1 (0.52) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8788976 | 0.80 | MAOA (0.47) | MAPTMAPK1SMN1; SMN2MAOAMEN1 | |
| SCHEMBL3910548 | 0.79 | ADORA2A (0.63) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL15158287 | 0.78 | MEN1 (0.45) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL29721704 | 0.78 | MAPT (0.61) | MAPTRAB9AMAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420861-B2 | Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD (US) | 2013-04-16 | — | — | US | disclosed |
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | CASP4, CASP8, CASP1 | MAPT 4707/4885RAB9A 2022/4885MAPK1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.