Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 1.00 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704600 | 0.89 | TAS1R3 (0.80) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL19387376 | 0.83 | ALDH1A1 (0.76) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL445824 | 0.81 | TAS1R3 (0.66) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL8401808 | 0.80 | TP53 (0.70) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL27107094 | 0.80 | NPC1 (0.78) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL28276389 | 0.80 | ALDH1A1 (0.70) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL28276388 | 0.80 | ALDH1A1 (0.70) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL705448 | 0.80 | TAS1R3 (1.00) | TAS1R3TAS1R1HDAC3 | |
| SCHEMBL28275043 | 0.79 | ALDH1A1 (1.00) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A | |
| SCHEMBL28275041 | 0.79 | ALDH1A1 (1.00) | TAS1R3TAS1R1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018161-A1 | METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION | AJINOMOTO CO. INC. (JP) | 2009-01-15 | — | — | US | claimed |
| CN-101316613-A | Gastrointestinal function promoter | AJINOMOTO KK (JP) | 2008-12-03 | — | — | CN | claimed |
| EP-1965832-A1 | GASTROINTESTINAL FUNCTION PROMOTER | Ajinomoto Co., Inc. (JP) | 2008-09-10 | — | — | EP | claimed |
| WO-2007052837-A1 | GASTROINTESTINAL FUNCTION PROMOTER | AJINOMOTO CO., INC. (JP) | 2007-05-10 | — | — | WO | claimed |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2022-03-08 | — | — | US | disclosed |
| US-20200225217-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED (US) | 2020-07-16 | — | — | US | disclosed |
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | SENOMYX, INC. | 2020-02-13 | — | — | US | disclosed |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2020-02-11 | — | — | US | disclosed |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | SENOMYX, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | SENOMYX, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| EP-1659881-B1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-1659881-B1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC (US) | 2019-04-03 | — | — | EP | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| CN-101316613-A | Gastrointestinal function promoter | AJINOMOTO KK (JP) | 2008-12-03 | — | — | CN | disclosed |
| EP-1965832-A1 | GASTROINTESTINAL FUNCTION PROMOTER | Ajinomoto Co., Inc. (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | SENOMYX, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20070104709-A1 | Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring | FIRMENICH INCORPORATED | 2007-05-10 | — | — | US | disclosed |
| US-20070104709-A1 | Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring | FIRMENICH INCORPORATED | 2007-05-10 | — | — | US | disclosed |
| WO-2007052837-A1 | GASTROINTESTINAL FUNCTION PROMOTER | AJINOMOTO CO., INC. (JP) | 2007-05-10 | — | — | WO | disclosed |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | FIRMENICH INCORPORATED | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885ALDH1A1 3409/4885 |
| US-20090018161-A1 | METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION | GIPR, GRPR, CCKBR | TAS1R3 84/4885TAS1R1 93/4885ALDH1A1 2743/4885 |
| US-20200225217-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R40 | TAS1R3 5/4885TAS1R1 2/4885ALDH1A1 1080/4885 |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | TAS1R3 5/4885TAS1R1 2/4885ALDH1A1 959/4885 |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885ALDH1A1 3409/4885 |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS2R40, TAS1R2, TAS1R1 | TAS1R3 5/4885TAS1R1 3/4885ALDH1A1 1037/4885 |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | TAS2R40, TAS2R4, TAS2R30 | TAS1R3 17/4885TAS1R1 11/4885ALDH1A1 1936/4885 |
| US-20070104709-A1 | Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring | TAS1R2, TAS1R3, TAS2R30 | TAS1R3 2/4885TAS1R1 4/4885ALDH1A1 2946/4885 |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | TAS1R3, TAS1R2, TAS2R30 | TAS1R3 1/4885TAS1R1 4/4885ALDH1A1 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.