Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943143 | 0.91 | RAB9A (0.51) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3943966 | 0.90 | RAB9A (0.43) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4345582 | 0.88 | HTR4 (0.45) | NPC1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4211749 | 0.86 | ACKR3 (0.44) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4212851 | 0.83 | RAB9A (0.49) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4029272 | 0.82 | RAB9A (0.50) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4199623 | 0.80 | RAB9A (0.52) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4353016 | 0.80 | HTR4 (0.45) | NPC1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4360682 | 0.78 | ALDH1A1 (0.46) | NPC1HTR2AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4347795 | 0.77 | HTR4 (0.41) | NPC1KMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |