Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168452 | 0.93 | CYP19A1 (0.45) | CYP19A1MEN1BLMKMT2AUSP2 | |
| SCHEMBL4198995 | 0.76 | MEN1 (0.37) | CYP19A1MEN1BLMKMT2AUSP2 | |
| SCHEMBL4194353 | 0.75 | CYP19A1 (0.32) | CYP19A1MEN1BLMKMT2AUSP2 | |
| SCHEMBL4200315 | 0.74 | KDM4E (0.42) | CYP19A1MEN1BLMKMT2AUSP2 | |
| SCHEMBL4186617 | 0.74 | ALDH1A1 (0.32) | CYP19A1MEN1BLMKMT2AUSP2 | |
| SCHEMBL4197474 | 0.72 | KDM4E (0.35) | CYP19A1MEN1BLMKMT2ANSD2 | |
| SCHEMBL4191708 | 0.72 | KMT2A (0.34) | MEN1BLMKMT2ALMNANSD2 | |
| SCHEMBL4187405 | 0.72 | ALDH1A1 (0.32) | MEN1KMT2AUSP2LMNATP53 | |
| SCHEMBL4191344 | 0.72 | DRD2 (0.36) | KMT2AMAPK1CYP3A4PTGS2DRD3 | |
| SCHEMBL11185373 | 0.71 | CYP19A1 (0.44) | CYP19A1MEN1BLMKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | CASP4, CASP8, CASP1 | CYP19A1 2871/4885MEN1 2002/4885BLM 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.