Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13697319 | 0.82 | CYP2C9 (0.41) | — | |
| SCHEMBL649663 | 0.80 | ALDH1A1 (0.46) | KDM1A | |
| SCHEMBL648469 | 0.79 | HPGD (0.41) | GPR119 | |
| SCHEMBL8866778 | 0.78 | GPR119 (0.42) | GPR119 | |
| SCHEMBL16502102 | 0.77 | CYP2C9 (0.39) | KDM1A | |
| SCHEMBL650151 | 0.75 | ALDH1A1 (0.41) | KDM1A | |
| SCHEMBL14836659 | 0.75 | CTSS (0.35) | CTSBCTSS | |
| SCHEMBL4197599 | 0.75 | CCR5 (0.44) | — | |
| SCHEMBL7700885 | 0.75 | GPR119 (0.39) | GPR119 | |
| SCHEMBL650593 | 0.74 | MEN1 (0.39) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CCR2 | GPR119 83/4885CTSL 2417/4885CTSB 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.