Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427884 | 0.84 | CA1 (0.48) | KMT2AMEN1GAAGFER | |
| SCHEMBL5556357 | 0.83 | PTGES2 (0.58) | GBA1KAT6AALDH1A1PTGES2SLC22A12 | |
| SCHEMBL1028459 | 0.82 | KAT6A (0.53) | GBA1KAT6AALDH1A1PSEN1PSEN2 | |
| SCHEMBL6239644 | 0.80 | CCR4 (0.46) | GBA1PTGES2 | |
| SCHEMBL6239903 | 0.80 | SLC40A1 (0.50) | GBA1KAT6AALDH1A1KMT2AEDNRA | |
| SCHEMBL8779451 | 0.80 | KAT6A (0.51) | GBA1KAT6AALDH1A1PSEN1PSEN2 | |
| SCHEMBL1621373 | 0.78 | ALDH1A1 (0.67) | GBA1KAT6AALDH1A1PSEN1PSEN2 | |
| SCHEMBL1767641 | 0.78 | CA1 (0.56) | GBA1KAT6AALDH1A1PSEN1PSEN2 | |
| SCHEMBL15973217 | 0.78 | KAT6A (0.50) | GBA1KAT6AALDH1A1PSEN1PSEN2 | |
| SCHEMBL24385370 | 0.77 | KAT6A (0.49) | GBA1KAT6AALDH1A1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320523-B1 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | WARNER-LAMBERT COMPANY LLC | 2005-01-06 | — | — | US | claimed |
| EP-1320523-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Warner-Lambert Company LLC (US) | 2003-06-25 | — | — | EP | claimed |
| WO-2002024672-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER-LAMBERT COMPANY LLC (US) | 2002-03-28 | — | — | WO | claimed |
| CN-119462587-A | Flavone-containing acylhydrazone compounds, and preparation method and application thereof | 贵州大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-118184582-A | 4-Seleno-1-benzenesulfonyl pyrazole compound and electrochemical synthesis method and application thereof | 延安大学 | 2024-06-14 | — | — | CN | disclosed |
| EP-4335439-A2 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-03-13 | — | — | EP | disclosed |
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| EP-4299135-A2 | BENZISOXAZOLE SULFONAMIDE DERIVATIVES | Pfizer Inc. (US) | 2024-01-03 | — | — | EP | disclosed |
| EP-3986890-B1 | BENZISOXAZOLE SULFONAMIDE DERIVATIVES | PFIZER (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20230357208-A1 | MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORS | Epizyme, Inc. (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230357208-A1 | MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORS | Epizyme, Inc. (US) | 2023-11-09 | — | — | US | disclosed |
| US-4327196-A | USING SULFONYL HYDRAZIDE BLOWING AGENTS, PEROXIDE CURING AGENTS FOR SIMULTANEOUS FOAMING AND CURING | UNIROYAL, INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4246422-A | Naphtholactam dyestuffs | CIBA-GEIGY AG (CH) | 1981-01-20 | — | — | US | disclosed |
| US-4246410-A | BENZINDOLE DYES OF YELLOW AND RED | CIBA -GEIGY AKTIENGESELLSCHAFT (CH) | 1981-01-20 | — | — | US | disclosed |
| US-4236007-A | YELLOW SHADES ON POLYESTERS | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-11-25 | — | — | US | disclosed |
| US-4180665-A | Substituted 3-benz(cd)indol-2-(1H)-ylidene-furo[2,3-b]quinoxalin-2(3H)one dyestuffs | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1979-12-25 | — | — | US | disclosed |
| US-4159379-A | Dispersion dyestuffs of the naphtholactam series | CIBA-GEIGY AG (CH) | 1979-06-26 | — | — | US | disclosed |
| US-4146541-A | YELLOW SHADE ON POLYESTERS | CIBA-GEIGY AG (CH) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357208-A1 | MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORS | EP300, KAT2A, KAT6A | GBA1 2596/4885KAT6A 3/4885ALDH1A1 2786/4885 |
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | BCAT1, BCAT2, ABAT | GBA1 247/4885KAT6A 1615/4885ALDH1A1 642/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | GBA1 102/4885KAT6A 951/4885ALDH1A1 744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.