SCHEMBL420700

SCHEMBL420700

C=Cc1cc(CC)cc(CC)c1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
PTGS2 P35354 4/20 0.34
TP53 P04637 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
TSHR P16473 1/20 0.32
PTGS1 P23219 2/20 0.31
ALOX5 P09917 1/20 0.31
TRPA1 O75762 1/20 0.31
CNR1 P21554 1/20 0.30
OPRM1 P35372 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25369680 0.89 ACHE (0.34) PTGS2RXRARXRBPTGS1ALOX5
SCHEMBL16961505 0.89 THRB (0.35) CNR1
SCHEMBL29900289 0.89
SCHEMBL11576875 0.89
SCHEMBL9652297 0.89
SCHEMBL25793173 0.86 RXRA (0.36) ALDH1A1PTGS2TP53TDP1RXRA
SCHEMBL395723 0.86 TP53 (0.43) ALDH1A1PTGS2TP53TDP1PTGS1
SCHEMBL21300387 0.85 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL16962598 0.85 NPC1 (0.41) ALDH1A1PTGS2TP53PTGS1
SCHEMBL21183425 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1996 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954989-A Functionalized polymer and preparation method and application thereof 中国石油化工股份有限公司 2025-05-09 CN claimed
CN-119954988-A Functionalized elastomer and preparation method and application thereof 中国石油化工股份有限公司 2025-05-09 CN claimed
EP-3822308-B1 RECYCLED RUBBER IND TECH RES INST (TW) 2025-03-05 EP claimed
CN-119552323-A Copolymer microgel latex, preparation method and application thereof 中国石油化工股份有限公司 2025-03-04 CN claimed
US-12195561-B2 Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers SYNTHOS S.A. (PL) 2025-01-14 US claimed
US-20240262940-A1 HYDROGENATION METHOD FOR AROMATIC POLYMER AND HYDROGENATED BLOCK COPOLYMER AND USE THEREOF Sinopec (Beijing) Research Institute of Chemical Industry Co., Ltd. (CN) 2024-08-08 US claimed
CN-118271496-A Isoalkenyl terpolymer containing oxygen polar groups and preparation method thereof 常州汉韦聚合物有限公司 2024-07-02 CN claimed
CN-114057937-B Conjugated diene polymer, preparation method and application thereof, and styrene-butadiene rubber 中国石油化工股份有限公司 2024-06-04 CN claimed
US-11993620-B2 Aminosilyl-functionalized conjugated dienes, their preparation and their use in the production of rubbers SYNTHOS S.A. (PL) 2024-05-28 US claimed
CN-118047997-A Dynamically vulcanized thermoplastic elastomer material composition, application thereof and dynamically vulcanized thermoplastic elastomer material 中国石油化工股份有限公司 2024-05-17 CN claimed
EP-1485911-A1 POLY(ARYLENE ETHER) DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2004-12-15 EP claimed
WO-2003079344-A1 POLY(ARYLENE ETHER) DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2003-09-25 WO claimed
US-20020094455-A1 Poly(arylene ether) data storage media SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-07-18 US claimed
US-20020049268-A1 Flame retardant molding compositions having improved flow WHITE ROGER J (US) 2002-04-25 US claimed
US-20010053838-A1 Terminal olefin functionalized macromonomers FMC CORPORATION 2001-12-20 US claimed
WO-2001070832-A2 TERMINAL OLEFIN FUNCTIONALIZED MACROMONOMERS FMC CORPORATION (US) 2001-09-27 WO claimed
US-5780551-A UNSYMMETRICALLY PROTECTED; FROM ONE OR MORE CONJUGATED DIENE OR ALKENYLAROMATIC COMPOUND FMC CORPORATION (US) 1998-07-14 US claimed
WO-1997016465-A1 TELECHELIC POLYMERS FROM MIXED INITIATOR FMC CORPORATION (US) 1997-05-09 WO claimed
US-4990386-A Terpolymer of aromatic vinyl monomer, cyclohexylmaleimide, and acrylic compound SHOWA DENKO KABUSHIKI KAISHI (JP) 1991-02-05 US claimed
US-4845154-A TIRE TREAD SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1989-07-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195561-B2 Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers CARM1, ILK, RIF1 ALDH1A1 473/4885PTGS2 1449/4885TP53 2131/4885
US-11993620-B2 Aminosilyl-functionalized conjugated dienes, their preparation and their use in the production of rubbers LTA, RALA, BOLA2; BOLA2B ALDH1A1 681/4885PTGS2 2183/4885TP53 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.