SCHEMBL4209812

SCHEMBL4209812

CNc1ccc(C(=O)O)c(NC)c1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 1/20 0.50
▸ AKR1C3 P42330 13/20 0.47
▸ AKR1C2 P52895 13/20 0.47
▸ MAPT P10636 1/20 0.45
▸ GRIK1 P39086 3/20 0.44
▸ MPO P05164 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400790 1.00 KDM4C (0.50) KDM4CAKR1C3AKR1C2MAPTGRIK1
SCHEMBL709947 0.83 HSD17B10 (0.47) KDM4CAKR1C3AKR1C2MAPTKDM4E
SCHEMBL143496 0.82 ALDH1A1 (0.40) KDM4CAKR1C3AKR1C2MAPTGRIK1
SCHEMBL31152563 0.82 ALDH1A1 (0.40) KDM4CAKR1C3AKR1C2MAPTGRIK1
SCHEMBL5158155 0.82 MAPT (0.49) AKR1C3MAPTKDM4EMEN1ALDH1A1
SCHEMBL21751026 0.81 KDM4E (0.59) MAPTKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL730081 0.80 KMT2A (0.57) MAPTKDM4EMEN1ALDH1A1KMT2A
SCHEMBL16421199 0.80 CLCN2 (0.53) KDM4CAKR1C3AKR1C2MAPTGRIK1
SCHEMBL2026958 0.80 HCAR3 (0.53) KDM4CAKR1C3AKR1C2MAPTKDM4E
SCHEMBL1706351 0.80 CYP1A2 (0.47) AKR1C3AKR1C2MAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11207645-B2 Composite semipermeable membrane and spiral wound separation membrane element NITTO DENKO CORPORATION (JP) 2021-12-28 — — US disclosed
CN-107428726-B Process for preparing optically active proton pump inhibitor compounds 国立大学法人东京大学 2021-03-16 — — CN disclosed
US-20200061548-A1 COMPOSITE SEMIPERMEABLE MEMBRANE AND SPIRAL WOUND SEPARATION MEMBRANE ELEMENT NITTO DENKO CORPORATION (JP) 2020-02-27 — — US disclosed
CN-105561377-B Degradable photocuring medical adhesive and preparation and application thereof 东华大学 2018-09-25 — — CN disclosed
CN-102498141-B Curable resin composition 太阳控股株式会社 2016-08-24 — — CN disclosed
US-20140294743-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES L'OREAL (FR) 2014-10-02 — — US disclosed
US-20090068129-A1 Aminophenylbenzothiazole compounds WAGNER BARBARA 2009-03-12 — — US disclosed
US-20080247976-A1 water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water DUEVA-KOGANOV OLGA V 2008-10-09 — — US disclosed
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer CIBA CORP. 2008-10-09 — — US disclosed
EP-0741332-B1 Photosensitive resin composition for sandblast resist MATSUSHITA ELECTRONICS CORP (JP) 2000-08-09 — — EP disclosed
US-5924912-A Photosensitive resin composition for sandblast resist MATSUSHITA ELECTRONICS CORPORATION (JP) 1999-07-20 — — US disclosed
US-5916738-A Photosensitive resin composition for sandblast resist MATSUSHITA ELECTRONICS CORPORATION (JP) 1999-06-29 — — US disclosed
US-5756261-A A CURABLE PHOTORESISTS BLENDS COMPRISING A POLYETHERURETHANE OR A POLYESTERURETHANE COPOLYMER WITH AN ACRYLIC COPOLYMER AND CARBOXY GROUP-CONTAINING CELLULOSE, A PHOTOINITIATOR; ADHESION, FLEXIBILITY, ELASTICITY MATSUSHITA ELECTRONICS CORPORATION (JP) 1998-05-26 — — US disclosed
EP-0741332-A1 Photosensitive resin composition for sandblast resist MATSUSHITA ELECTRONICS CORPORATION (JP) 1996-11-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080247976-A1 water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water CUTA, POLR1C, MSH6 KDM4C 3414/4885AKR1C3 2164/4885AKR1C2 1658/4885
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer MSH6, CUTA, ERCC5 KDM4C 2650/4885AKR1C3 1546/4885AKR1C2 1411/4885
US-20090068129-A1 Aminophenylbenzothiazole compounds C1S, C5, C9 KDM4C 673/4885AKR1C3 103/4885AKR1C2 471/4885
US-20140294743-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES KRT18, LAGE3, TYR KDM4C 99/4885AKR1C3 166/4885AKR1C2 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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